ID   A0A3B4FIW8_9CICH        Unreviewed;       495 AA.
AC   A0A3B4FIW8;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   SubName: Full=TUB bipartite transcription factor {ECO:0000313|Ensembl:ENSPNYP00000010520.1};
GN   Name=TUB {ECO:0000313|Ensembl:ENSPNYP00000010520.1};
OS   Pundamilia nyererei.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Pundamilia.
OX   NCBI_TaxID=303518 {ECO:0000313|Ensembl:ENSPNYP00000010520.1, ECO:0000313|Proteomes:UP000261460};
RN   [1] {ECO:0000313|Ensembl:ENSPNYP00000010520.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- SIMILARITY: Belongs to the TUB family. {ECO:0000256|ARBA:ARBA00007129}.
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DR   AlphaFoldDB; A0A3B4FIW8; -.
DR   STRING; 303518.ENSPNYP00000010520; -.
DR   Ensembl; ENSPNYT00000010776.1; ENSPNYP00000010520.1; ENSPNYG00000007978.1.
DR   GeneTree; ENSGT00940000158372; -.
DR   Proteomes; UP000261460; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR025659; Tubby-like_C.
DR   InterPro; IPR000007; Tubby_C.
DR   InterPro; IPR018066; Tubby_C_CS.
DR   InterPro; IPR005398; Tubby_N.
DR   PANTHER; PTHR16517:SF20; TUBBY PROTEIN HOMOLOG; 1.
DR   PANTHER; PTHR16517; TUBBY-RELATED; 1.
DR   Pfam; PF01167; Tub; 1.
DR   Pfam; PF16322; Tub_N; 1.
DR   PRINTS; PR01573; SUPERTUBBY.
DR   PRINTS; PR01574; TUBBYPROTEIN.
DR   SUPFAM; SSF54518; Tubby C-terminal domain-like; 1.
DR   PROSITE; PS01200; TUB_1; 1.
PE   3: Inferred from homology;
KW   Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT   DOMAIN          34..232
FT                   /note="Tubby N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16322"
FT   DOMAIN          250..492
FT                   /note="Tubby C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01167"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          39..176
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          188..242
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        74..90
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        123..139
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        203..229
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   495 AA;  55793 MW;  53055D1A42D018D3 CRC64;
     MEGVSSNRSM SYSRWSYDTL DDEGTNLRQQ KLDRQRALLE QKQKKKRQEP LMVQSNVDGR
     SRTRRAKQSE EQAPLVESYL SSNSSTIYHQ EAEQEEVKVM SDPQPPRSAK KGKASASSTP
     QTGSEKKERK GKHKIDGLAS QQDDSQIQIL TVGHPTSEEA EAEPVMSCTQ SQSKQDLRVT
     MLKKISSSMN FDEEEDDDDE ISSSSSQLNS NTRPGSATSK KSSKEVASAP TPPVSEPAID
     VDDLEEFSLR PAPQGVRVKC RITRDKKGMD RGMYPTYYLH LEREDGKKVF LLAGRKRKKS
     KTSNYLISID PTDLSRGGES FIGKLRSNLM GTKFTVYDNG LNPMKSTTSL EATNLRQELA
     AICYETNVLG FKGPRKMSVI IPGMNMDHER VSIRPRNDHE SLLARWQNKN TESVIELHNK
     TPVWNDDTQS YVLNFHGRVT QASVKNFQII HDNDDYIVMQ FGRVAEDVFT MDYNYPMCAL
     QAFAIALSSF DSKLA
//