ID A0A3B4FJS2_9CICH Unreviewed; 603 AA.
AC A0A3B4FJS2;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Netrin-1-like {ECO:0000313|Ensembl:ENSPNYP00000009431.1};
OS Pundamilia nyererei.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Pundamilia.
OX NCBI_TaxID=303518 {ECO:0000313|Ensembl:ENSPNYP00000009431.1, ECO:0000313|Proteomes:UP000261460};
RN [1] {ECO:0000313|Ensembl:ENSPNYP00000009431.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00460}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3B4FJS2; -.
DR Ensembl; ENSPNYT00000009648.1; ENSPNYP00000009431.1; ENSPNYG00000006948.1.
DR GeneTree; ENSGT00940000166316; -.
DR Proteomes; UP000261460; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR CDD; cd00055; EGF_Lam; 3.
DR CDD; cd03579; NTR_netrin-1_like; 1.
DR Gene3D; 2.40.50.120; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR InterPro; IPR008211; Laminin_N.
DR InterPro; IPR002049; LE_dom.
DR InterPro; IPR001134; Netrin_domain.
DR InterPro; IPR018933; Netrin_module_non-TIMP.
DR InterPro; IPR008993; TIMP-like_OB-fold.
DR PANTHER; PTHR10574:SF443; -; 1.
DR PANTHER; PTHR10574; NETRIN/LAMININ-RELATED; 1.
DR Pfam; PF00053; Laminin_EGF; 3.
DR Pfam; PF00055; Laminin_N; 1.
DR Pfam; PF01759; NTR; 1.
DR SMART; SM00643; C345C; 1.
DR SMART; SM00180; EGF_Lam; 3.
DR SMART; SM00136; LamNT; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 3.
DR SUPFAM; SSF50242; TIMP-like; 1.
DR PROSITE; PS01248; EGF_LAM_1; 1.
DR PROSITE; PS50027; EGF_LAM_2; 3.
DR PROSITE; PS51117; LAMININ_NTER; 1.
DR PROSITE; PS50189; NTR; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00460};
KW Laminin EGF-like domain {ECO:0000256|ARBA:ARBA00023292,
KW ECO:0000256|PROSITE-ProRule:PRU00460};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..33
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 34..603
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017304384"
FT DOMAIN 52..257
FT /note="Laminin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51117"
FT DOMAIN 258..313
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 314..376
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 377..426
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 440..574
FT /note="NTR"
FT /evidence="ECO:0000259|PROSITE:PS50189"
FT DISULFID 260..277
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 279..288
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 344..353
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 377..389
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 379..396
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 398..407
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 410..424
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
SQ SEQUENCE 603 AA; 68216 MW; 4C101B8EFAD4A3BB CRC64;
MFQPFSPPPS TSFCPVFLLL LFLCLSLISS SLPQPPLSWN SPNDPCYHTV GRPRHCLSEF
INAAYGVPVN VNHSLQGNDY DSHITTLTDL NNPHNLTCWM ADAGTDTGDW VLTLPLGRRF
EITYISFQFC HQKEPLDPIS ISILKSMDFG RTWRPMQHYS SDCLRNFKLP SQTVAQTRHQ
ETEPLCSDPR PLQKQRGGMV LAFSTLDGRP SSPDFDYSPT LQDWVTATDI RVVFHKVSSE
PPGRAPFALS DLQVGGRCKC NGHASRCRRD DTGRAVCVCK HHTAGPDCDV CEDFYFDRPW
HRATPTNPNP CVACECNGHS NKCRFSMEVF QQSGRRSGGV CQKCRHHTAG RHCQYCQNGY
TRNHKKPLSH RKACQPCQCH PVGAVGGWCN QTSGQCLCRR GVTGLRCNRC APGYEQGKSP
LQPCIRKFTG HADVHFKPEC VSYCQPSQVK VKMNLETYCR KNYVLKVQVK GMERSGPWWQ
FSILVQVVFR TGSHARIRRG SQSLWVPDRD LGCGCPALQV GRTVLLIGAD EGEQPWVPEE
KRLVADRSTL APQWQEHWSP KLRAFRGQDK RGRCEKKAQR NPSTPKHIPT FRFMYILKRL
IIA
//
