ID A0A3B4FN06_9CICH Unreviewed; 516 AA.
AC A0A3B4FN06;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Aminopeptidase W07G4.4 {ECO:0000313|Ensembl:ENSPNYP00000011980.1, ECO:0000313|RefSeq:XP_013767630.1};
GN Name=LOC102212542 {ECO:0000313|RefSeq:XP_013767630.1};
OS Pundamilia nyererei.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Pundamilia.
OX NCBI_TaxID=303518 {ECO:0000313|Ensembl:ENSPNYP00000011980.1, ECO:0000313|Proteomes:UP000261460};
RN [1] {ECO:0000313|Ensembl:ENSPNYP00000011980.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_013767630.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the peptidase M17 family.
CC {ECO:0000256|ARBA:ARBA00009528}.
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DR RefSeq; XP_013767630.1; XM_013912176.1.
DR AlphaFoldDB; A0A3B4FN06; -.
DR STRING; 303518.ENSPNYP00000011980; -.
DR Ensembl; ENSPNYT00000012270.1; ENSPNYP00000011980.1; ENSPNYG00000009066.1.
DR GeneID; 102212542; -.
DR GeneTree; ENSGT00530000063255; -.
DR OrthoDB; 1329669at2759; -.
DR Proteomes; UP000261460; Unplaced.
DR Proteomes; UP000695023; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00433; Peptidase_M17; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR011356; Leucine_aapep/pepB.
DR InterPro; IPR000819; Peptidase_M17_C.
DR PANTHER; PTHR11963; LEUCINE AMINOPEPTIDASE-RELATED; 1.
DR PANTHER; PTHR11963:SF23; ZGC:152830; 1.
DR Pfam; PF00883; Peptidase_M17; 1.
DR PRINTS; PR00481; LAMNOPPTDASE.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
DR PROSITE; PS00631; CYTOSOL_AP; 1.
PE 3: Inferred from homology;
KW Aminopeptidase {ECO:0000256|ARBA:ARBA00022438,
KW ECO:0000313|RefSeq:XP_013767630.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000695023}.
FT DOMAIN 345..352
FT /note="Cytosol aminopeptidase"
FT /evidence="ECO:0000259|PROSITE:PS00631"
SQ SEQUENCE 516 AA; 55728 MW; 0FB6D4CAB5DD1736 CRC64;
MCTSVQPIQW TSDLRNQNFD GIVLVTQSHE SLPSELESLK APLQDYSAVD SGLGEEVVVI
KVPGLPGNRL VFASTGPVNR DYDDIRRFSD AAVNGIQRAL KAGMQRPLLV CPPHADYKNN
TLVAALGALH ALYMPLEVRE SNVKKNDHKV CVLGLWAAEE ARGTKLVELA NALENGRLAY
RDIGGSDPER MAAPRVADYV QELFKDSPVK VEVVSDLKTL EKEYPCLAAV NRCANSVPRH
QARVVKLQYC GEGPIEKTLM LVGKGITYDT GGADIKAGGI MAGMHRDKCG AAAVAGFFQI
VAQLKPQHLK VVGVMAMVRN SVGADCYVAD ELVVSRAGRR VRVGNTDAEG RMVMVDLLCE
MKEKAVNEVS PQLFTIATLT GHAIRAMGPN YSIIMDNGPA HRSGNAAQWQ KAGEVLGDLF
EVSTIRREDY EFHKGQSEYE DILQCNNLPS SATPRGHQTP AAFLIMASGL DKHGVDSEAP
LPYSHIDIAG SSGPFPGVPT GAPIVTMATN YILSDL
//
