ID A0A3B4FNM5_9CICH Unreviewed; 551 AA.
AC A0A3B4FNM5;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Ankyrin repeat and SOCS box containing 15 {ECO:0000313|Ensembl:ENSPNYP00000012137.1};
OS Pundamilia nyererei.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Pundamilia.
OX NCBI_TaxID=303518 {ECO:0000313|Ensembl:ENSPNYP00000012137.1, ECO:0000313|Proteomes:UP000261460};
RN [1] {ECO:0000313|Ensembl:ENSPNYP00000012137.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
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DR AlphaFoldDB; A0A3B4FNM5; -.
DR STRING; 303518.ENSPNYP00000012137; -.
DR Ensembl; ENSPNYT00000012432.1; ENSPNYP00000012137.1; ENSPNYG00000009179.1.
DR GeneTree; ENSGT00940000157073; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000261460; Unplaced.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 3.
DR Gene3D; 1.10.750.20; SOCS box; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR001496; SOCS_box.
DR InterPro; IPR036036; SOCS_box-like_dom_sf.
DR PANTHER; PTHR24133; ANKYRIN DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR24133:SF42; ANKYRIN REPEAT AND SOCS BOX-CONTAINING 3; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF13637; Ank_4; 1.
DR Pfam; PF07525; SOCS_box; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 11.
DR SMART; SM00253; SOCS; 1.
DR SMART; SM00969; SOCS_box; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF158235; SOCS box-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 4.
DR PROSITE; PS50088; ANK_REPEAT; 5.
DR PROSITE; PS50225; SOCS; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 102..134
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 168..200
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 201..233
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 233..265
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 298..330
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 498..543
FT /note="SOCS box"
FT /evidence="ECO:0000259|PROSITE:PS50225"
SQ SEQUENCE 551 AA; 60786 MW; 1EBD083FB139F016 CRC64;
MDDFEQEAIN EDLIEFAVRE SIQDAYKLPC SVQTDSLLVA LVCILAGDVD ALQELSGCAS
AFRESDSRGW LPLHAAAVQL LNGVLVAVLE STDLTLEEQT EDGDTALTLA AEAGQVENIK
LLLKHGASPH NNNSRNESPL LIAVRQRSYD MVLSLIMGGA FVEQVCLTKW RAIHEAAKEG
CAAIMMLLLR HGAKITSRDG HGVTPLGIAA EHGNSEVLDI LIHHGKTVYV ASNGDTVLYD
ATGSGNLDCV KLLLEHGANP NVASYACQLP IHRAAYEGYI LILRTLIPIT TKRAIRLSGQ
SPVHSAADGG QVQCLELLIQ KGYDVNALLH NYGDLRKTPL YFAVSNGDVT CSERLLAAGA
RTDLDPLRCI LVAIRAERFD LVELLLSHGA EVNCYFRVIS NTVFPTALQY CFRDHVMLRL
LLNSGYHSIF DLFTEDIQPK VISFCDFVSV SCLAHVVGKV VRMLLDYVSH VSICFKLRQI
LQRRPEWDEI SDILGKTPRS LQHLCRLVIR SHMSLRTLND PETMAAGPFP PRLMSYLTYR
ERDLYGDLLS V
//
