ID A0A3B4FUD6_9CICH Unreviewed; 418 AA.
AC A0A3B4FUD6;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Arrestin domain-containing protein 3 {ECO:0000256|ARBA:ARBA00041132};
GN Name=LOC102204790 {ECO:0000313|RefSeq:XP_005739195.1};
OS Pundamilia nyererei.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Pundamilia.
OX NCBI_TaxID=303518 {ECO:0000313|Ensembl:ENSPNYP00000014182.1, ECO:0000313|Proteomes:UP000261460};
RN [1] {ECO:0000313|Ensembl:ENSPNYP00000014182.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_005739195.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004413};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004413};
CC Cytoplasmic side {ECO:0000256|ARBA:ARBA00004413}. Cytoplasm
CC {ECO:0000256|ARBA:ARBA00004496}. Early endosome
CC {ECO:0000256|ARBA:ARBA00004412}. Endosome
CC {ECO:0000256|ARBA:ARBA00004177}. Lysosome
CC {ECO:0000256|ARBA:ARBA00004371}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
CC -!- SIMILARITY: Belongs to the arrestin family.
CC {ECO:0000256|ARBA:ARBA00005298}.
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DR RefSeq; XP_005739195.1; XM_005739138.1.
DR AlphaFoldDB; A0A3B4FUD6; -.
DR STRING; 303518.ENSPNYP00000014182; -.
DR Ensembl; ENSPNYT00000014536.1; ENSPNYP00000014182.1; ENSPNYG00000010736.1.
DR GeneID; 102204790; -.
DR GeneTree; ENSGT00940000155411; -.
DR OrthoDB; 22053at2759; -.
DR Proteomes; UP000261460; Unplaced.
DR Proteomes; UP000695023; Unplaced.
DR GO; GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 2.60.40.640; -; 2.
DR InterPro; IPR014752; Arrestin-like_C.
DR InterPro; IPR011021; Arrestin-like_N.
DR InterPro; IPR011022; Arrestin_C-like.
DR InterPro; IPR014756; Ig_E-set.
DR PANTHER; PTHR11188; ARRESTIN DOMAIN CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11188:SF49; ARRESTIN DOMAIN-CONTAINING PROTEIN 3; 1.
DR Pfam; PF02752; Arrestin_C; 1.
DR Pfam; PF00339; Arrestin_N; 1.
DR SMART; SM01017; Arrestin_C; 1.
DR SUPFAM; SSF81296; E set domains; 2.
PE 3: Inferred from homology;
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Lysosome {ECO:0000256|ARBA:ARBA00023228};
KW Reference proteome {ECO:0000313|Proteomes:UP000695023};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 187..314
FT /note="Arrestin C-terminal-like"
FT /evidence="ECO:0000259|SMART:SM01017"
FT REGION 395..418
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 418 AA; 46311 MW; 0844DAF8E0BC27C8 CRC64;
MVLSKVRALA IYFDSLNENN LPVFSGGDLV SGRVVVEVTG DVRVKSLDIT ARGVAKVRWT
ESRNAGANTA YTQNYTEEVE YLHHYDTLIG EERDEDCPEE GVTVLHPGLH EFAFSFNLPQ
MALATSFEGK HGSVRYWVKA ELHRPWLLPV KVKKEFIVFE HIDINTPLLL APQAGTKEKT
LCCWFCASGP ISLSAKIERK GYTPGESIQI FAEVENCSSR VVVPKAALYQ TQTFFAKGKG
KEIQQLVSNV RGDPLPQGKS QSWEGKLLKI PPVSPSILDC PIIKVEYALV VYVDIPGGLN
LSLSLPLVIG TIPLHACTTR TSSISSNCST LSWLGLPERP EAPPSYSELA ISESHRQDYL
QGCDRSDAEG EDRGSLLTYI TEFRYLPPPL YSEVDPYPDP LEVQGTVEVR RPDTCPSR
//
