ID A0A3B4FWU7_9CICH Unreviewed; 451 AA.
AC A0A3B4FWU7;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Glycerol-3-phosphate acyltransferase 3 {ECO:0000313|Ensembl:ENSPNYP00000014068.1, ECO:0000313|RefSeq:XP_005748457.1};
GN Name=gpat3 {ECO:0000313|RefSeq:XP_005748457.1};
OS Pundamilia nyererei.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Pundamilia.
OX NCBI_TaxID=303518 {ECO:0000313|Ensembl:ENSPNYP00000014068.1, ECO:0000313|Proteomes:UP000261460};
RN [1] {ECO:0000313|Ensembl:ENSPNYP00000014068.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_005748457.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Glycerolipid metabolism; triacylglycerol biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004771}.
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- PATHWAY: Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-
CC diacylglycerol from sn-glycerol 3-phosphate: step 1/3.
CC {ECO:0000256|ARBA:ARBA00004765}.
CC -!- SIMILARITY: Belongs to the 1-acyl-sn-glycerol-3-phosphate
CC acyltransferase family. {ECO:0000256|ARBA:ARBA00008655}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_005748457.1; XM_005748400.1.
DR AlphaFoldDB; A0A3B4FWU7; -.
DR STRING; 303518.ENSPNYP00000014068; -.
DR Ensembl; ENSPNYT00000014418.1; ENSPNYP00000014068.1; ENSPNYG00000010667.1.
DR GeneID; 102196314; -.
DR CTD; 84803; -.
DR GeneTree; ENSGT01030000234574; -.
DR OrthoDB; 1080at2759; -.
DR Proteomes; UP000261460; Unplaced.
DR Proteomes; UP000695023; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008374; F:O-acyltransferase activity; IEA:InterPro.
DR CDD; cd07991; LPLAT_LPCAT1-like; 1.
DR InterPro; IPR045252; LPCAT1-like.
DR InterPro; IPR002123; Plipid/glycerol_acylTrfase.
DR PANTHER; PTHR23063:SF10; GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 3; 1.
DR PANTHER; PTHR23063; PHOSPHOLIPID ACYLTRANSFERASE; 1.
DR Pfam; PF01553; Acyltransferase; 1.
DR SMART; SM00563; PlsC; 1.
DR SUPFAM; SSF69593; Glycerol-3-phosphate (1)-acyltransferase; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000313|RefSeq:XP_005748457.1};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000695023};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 144..162
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 168..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 230..341
FT /note="Phospholipid/glycerol acyltransferase"
FT /evidence="ECO:0000259|SMART:SM00563"
SQ SEQUENCE 451 AA; 51102 MW; 744AA5356A861022 CRC64;
MEDLWTVAVA VFQLWIFVVV FFITLPAMFG LSLGVTSVYI QILVKLLEWA TIRIQRGREE
QPSVPAPLPN GIIERAEGSM EEEMEQLRRS RSLEGGEFAL SDALYFCKKG LESIVDDQVT
QRFSSEELAS WNLLTRTNQN FRYISLRLTI FWGIGVFVRY CVLFPLRITL AIIGLSWLVI
GTTLVGFLPE NSVKYWLSEV VHLTCYRICA RALSATIRYH NKENRPQKGG ICVANHTTPI
DVVILANDGC YAMVGQIHGG LMGVIQRSMV RSCPHVWFER SEMKDRHAVT SRLRAHVAAK
TKLPILIFPE GTCINNTSVM MFKKGSFEIG GTIHPVAIKY DPRLGDAFWN SSKYNMVSYL
LRTMTSWAIV VNVWYLPPMT IQDGEDAVQF ANRVKSAVAC RGGLLDLAWD GSLKRGKVKD
AYKEEQQKMY SRVIVRQNSI SATHTRRDDQ S
//
