ID   A0A3B4FX92_9CICH        Unreviewed;       324 AA.
AC   A0A3B4FX92;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=Septin-5 {ECO:0000256|ARBA:ARBA00018908};
GN   Name=SEPTIN5 {ECO:0000313|Ensembl:ENSPNYP00000013936.1};
OS   Pundamilia nyererei.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Pundamilia.
OX   NCBI_TaxID=303518 {ECO:0000313|Ensembl:ENSPNYP00000013936.1, ECO:0000313|Proteomes:UP000261460};
RN   [1] {ECO:0000313|Ensembl:ENSPNYP00000013936.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC       {ECO:0000256|ARBA:ARBA00004245}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC       GTPase superfamily. Septin GTPase family.
CC       {ECO:0000256|RuleBase:RU004560}.
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DR   AlphaFoldDB; A0A3B4FX92; -.
DR   Ensembl; ENSPNYT00000014283.1; ENSPNYP00000013936.1; ENSPNYG00000010341.1.
DR   GeneTree; ENSGT00940000159913; -.
DR   Proteomes; UP000261460; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   CDD; cd01850; CDC_Septin; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR030379; G_SEPTIN_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR016491; Septin.
DR   PANTHER; PTHR18884; SEPTIN; 1.
DR   PANTHER; PTHR18884:SF68; SEPTIN-5; 1.
DR   Pfam; PF00735; Septin; 1.
DR   PIRSF; PIRSF006698; Septin; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51719; G_SEPTIN; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|PIRSR:PIRSR006698-
KW   2}; Methylation {ECO:0000256|ARBA:ARBA00022481};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|PIRSR:PIRSR006698-2}.
FT   DOMAIN          32..304
FT                   /note="Septin-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51719"
FT   SITE            153
FT                   /note="Important for dimerization"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR006698-2"
SQ   SEQUENCE   324 AA;  37531 MW;  B92430DD772177C3 CRC64;
     KPKSLGWEPL HLGEYVGFAT LPNQLHRKSV KKGFDFTLLV AGESGLGKST LVNSLFLTDL
     HKDRKLLNAE ERISQTVEIT KHTVDIEEKG VKLKLTIVDT PGFGDAVNNT AWRPITDYID
     QQFEQYFRDE SGLNRKNIQD NRVHCCLYFI PPFGHGLHPV DIEFMKALQD KVNVVPLIAK
     ADCLTPFEIK KLKERVREEI DKYGIKIYQF PHCDSDEDEE FKQQDKELKE STPFAVIGSN
     TVVEARGHRV RGRVYPWGIV EVENPSHCDF VKLRTMLIRT HMHDLKDITS DCHYENYRAQ
     CIQNMTRCEP DKTYTWSQNM VNYE
//