ID   A0A3B4G239_9CICH        Unreviewed;       530 AA.
AC   A0A3B4G239;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Perforin-1-like {ECO:0000313|Ensembl:ENSPNYP00000015641.1};
OS   Pundamilia nyererei.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Pundamilia.
OX   NCBI_TaxID=303518 {ECO:0000313|Ensembl:ENSPNYP00000015641.1, ECO:0000313|Proteomes:UP000261460};
RN   [1] {ECO:0000313|Ensembl:ENSPNYP00000015641.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B4G239; -.
DR   Ensembl; ENSPNYT00000016042.1; ENSPNYP00000015641.1; ENSPNYG00000011800.1.
DR   GeneTree; ENSGT00940000164067; -.
DR   Proteomes; UP000261460; Unplaced.
DR   Gene3D; 2.60.40.150; C2 domain; 1.
DR   InterPro; IPR000008; C2_dom.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR020864; MACPF.
DR   PANTHER; PTHR46096:SF5; PERFORIN 1.3-RELATED; 1.
DR   PANTHER; PTHR46096; PERFORIN-1; 1.
DR   Pfam; PF00168; C2; 1.
DR   Pfam; PF01823; MACPF; 1.
DR   SMART; SM00239; C2; 1.
DR   SMART; SM00457; MACPF; 1.
DR   SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR   PROSITE; PS50004; C2; 1.
DR   PROSITE; PS51412; MACPF_2; 1.
PE   4: Predicted;
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           17..530
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5017291553"
FT   DOMAIN          21..351
FT                   /note="MACPF"
FT                   /evidence="ECO:0000259|PROSITE:PS51412"
FT   DOMAIN          370..488
FT                   /note="C2"
FT                   /evidence="ECO:0000259|PROSITE:PS50004"
SQ   SEQUENCE   530 AA;  58817 MW;  CA61ACED799E81FB CRC64;
     MLSSFLLLVF LPLCLGCQTS SFTECQKVPF VPGHNLVGEG FDVVKLQTSG ALVVNVKDYM
     VGGAQGNCTV CHNRLLNQIQ KLPVSVLDWR IKVSTFTRFI YYHVSCFWYT SSQVGLGIKG
     IAGVAIGGSH SMSSTFAESR SRSDKFSFTS HEFKCKYYTF RLHSRPPLSK EFEVSLKNLP
     STYDHKNTSA FRQFISIYGT HFIRRVQLGG RVHSMTAIRT CQTSMSGLSI QAVSTCLSAE
     ASATIKGIPV HASSEFCRRK SKSLKTASTF SAAFSDRKTQ VLGGDGGITD ILFNPRGSEG
     YKKWLASLKS VPGVVSYQIS PLHLLIRDNP ILKASLRDAI SDYILTSAKP LHCPVNCKIG
     HRKQNCACQC QGHRMVDSHC CPAAAGVAQM NVTVVRAEAL WGDYFSKTDG YVKVFYNNQG
     GTTPVIWNNN FPQWNYLFTF GSINLKERKP VVFEVWDRDS IWDDDLLGKV SVIPTMGRNI
     NKKFKLKHGS VLVRLSVVCG PSLEGSLCER YIPSPTYQDV MGYAKNHQGY
//