ID   A0A3B4G443_9CICH        Unreviewed;       408 AA.
AC   A0A3B4G443;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Metabolism of cobalamin associated A {ECO:0000313|Ensembl:ENSPNYP00000016508.1};
DE   SubName: Full=Methylmalonic aciduria type A protein, mitochondrial {ECO:0000313|RefSeq:XP_005727004.1};
GN   Name=mmaa {ECO:0000313|RefSeq:XP_005727004.1};
OS   Pundamilia nyererei.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Pundamilia.
OX   NCBI_TaxID=303518 {ECO:0000313|Ensembl:ENSPNYP00000016508.1, ECO:0000313|Proteomes:UP000261460};
RN   [1] {ECO:0000313|Ensembl:ENSPNYP00000016508.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
RN   [2] {ECO:0000313|RefSeq:XP_005727004.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB
CC       subfamily. {ECO:0000256|ARBA:ARBA00009625}.
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DR   RefSeq; XP_005727004.1; XM_005726947.1.
DR   AlphaFoldDB; A0A3B4G443; -.
DR   STRING; 303518.ENSPNYP00000016508; -.
DR   Ensembl; ENSPNYT00000016918.1; ENSPNYP00000016508.1; ENSPNYG00000012505.1.
DR   GeneID; 102194396; -.
DR   CTD; 166785; -.
DR   GeneTree; ENSGT00390000009908; -.
DR   OrthoDB; 159517at2759; -.
DR   Proteomes; UP000261460; Unplaced.
DR   Proteomes; UP000695023; Unplaced.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   CDD; cd03114; MMAA-like; 1.
DR   Gene3D; 1.10.287.130; -; 1.
DR   Gene3D; 1.20.5.170; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR005129; GTPase_ArgK.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   NCBIfam; TIGR00750; lao; 1.
DR   PANTHER; PTHR23408:SF3; METHYLMALONIC ACIDURIA TYPE A PROTEIN, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR23408; METHYLMALONYL-COA MUTASE; 1.
DR   Pfam; PF03308; MeaB; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000695023}.
SQ   SEQUENCE   408 AA;  44342 MW;  B2BB48C6DAC44F5B CRC64;
     MRQFSLALLR HISSSTAPAL TGTCRLHSWH CFTASRPQYR SIVPPHSCQH TRTESAAASQ
     HIQDLSGPEQ RLLNKLYDGL IGGQRASLAE CITLVETQHP RKKELAQVLL QRVLAYRREQ
     ESRNGGKPVA FRVGLSGPPG AGKSSFIEVV GKMLTGRGHK VAVLAVDPSS CTTGGSLMGD
     KTRMTELSRD MNAFIRPSPT SGTLGGVTRT TNEAIVLCEG AGYDIVLVET VGVGQSEFAV
     ADMVDMFVLL IPPAGGDELQ GIKRGIIERA ELVVVTKSDG DLVVPARRIQ AEYTSALKLL
     RRQSKSWNPK VVRASSQTFE GIPEVWAKME AYREAALASG ELQGRRTAQQ KVWMWSLIQE
     SVLCHFQNHP GVREALPHLE ERVTKGAISP GLAADLLLRA FSSSSSSQ
//