ID A0A3B4G6J5_9CICH Unreviewed; 644 AA.
AC A0A3B4G6J5;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Forkhead box protein O6-like {ECO:0000313|Ensembl:ENSPNYP00000018515.1, ECO:0000313|RefSeq:XP_005723095.1};
GN Name=FOXO4 {ECO:0000313|Ensembl:ENSPNYP00000018515.1};
GN Synonyms=LOC102216178 {ECO:0000313|RefSeq:XP_005723095.1,
GN ECO:0000313|RefSeq:XP_005723096.1, ECO:0000313|RefSeq:XP_005723097.1,
GN ECO:0000313|RefSeq:XP_005723098.1};
OS Pundamilia nyererei.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Pundamilia.
OX NCBI_TaxID=303518 {ECO:0000313|Ensembl:ENSPNYP00000018515.1, ECO:0000313|Proteomes:UP000261460};
RN [1] {ECO:0000313|Ensembl:ENSPNYP00000018515.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_005723095.1, ECO:0000313|RefSeq:XP_005723096.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089}.
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DR RefSeq; XP_005723095.1; XM_005723038.1.
DR RefSeq; XP_005723096.1; XM_005723039.1.
DR RefSeq; XP_005723097.1; XM_005723040.1.
DR RefSeq; XP_005723098.1; XM_005723041.1.
DR AlphaFoldDB; A0A3B4G6J5; -.
DR STRING; 303518.ENSPNYP00000018515; -.
DR Ensembl; ENSPNYT00000018978.1; ENSPNYP00000018515.1; ENSPNYG00000014002.1.
DR GeneID; 102216178; -.
DR CTD; 4303; -.
DR GeneTree; ENSGT00940000159334; -.
DR OrthoDB; 5385885at2759; -.
DR Proteomes; UP000261460; Unplaced.
DR Proteomes; UP000695023; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd20062; FH_FOXO4; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR047409; FH_FOXO4.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR032067; FOXO-TAD.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR45767; FORKHEAD BOX PROTEIN O; 1.
DR PANTHER; PTHR45767:SF3; FORKHEAD BOX PROTEIN O4; 1.
DR Pfam; PF00250; Forkhead; 1.
DR Pfam; PF16676; FOXO-TAD; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00658; FORK_HEAD_2; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089};
KW Reference proteome {ECO:0000313|Proteomes:UP000695023}.
FT DOMAIN 98..192
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 98..192
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 1..73
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 175..304
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 335..425
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 492..522
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 624..644
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 235..288
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 359..425
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 628..644
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 644 AA; 67774 MW; 131116A58405ECBF CRC64;
MEESPVPPID PDFEPQSRPR SCTWPLPRPD ITAVKSEGAD GAESAATTPP ADEDKPEPQQ
IASEPEKAAA ASVEGGVVAG VGGTGATPRK GSSRRNAWGN QSYADLISQA IENSPEKRLT
LAQIYEWMVK TVPYFRDKGD SNSSAGWKNS IRHNLSLHNK FLRVHNESTG KSSWWMLNPE
GGKTGKAPRR RAASMDNSSK LLKSRMRAKQ TKKQAGAAGL GGTAGVLQGD GATGSAGADS
PNSSQQFSKW GVNSSSPSSR GSLDDTDMWT TFRPRTSSNA STLSGRLSPI APGQEDDDNL
PDDGLLGRFS ASNLTPTLTE TLMEELDLID GLTLMTGQQG GASPSTAPPA PPTPLPSAST
LLPRGSSFPS FHQLSSSLPQ APTHTRATTS VSPCGPGSKE QTTFSNSLFN PMPTPSSRGS
GHYSAHVPSS LEALLTSDSP PPSDVLMAQV DSIMPNSGGV GMIGLGTSVA GVRLAKGLEP
NTVSPIGLQA QMQPQQHHLH HQQQQQPPPP AQQQQQQHQH HSQMELGMIL SGLSQDPSQL
SALKAQHAAL PAVGSQHGGP ITTLPGISQF GVPSCFPTGP GRLPTDLDID MFTENLDCDV
DYIINSDLMD GDGLDFNFDP MLPGGQGYPG PTTTQGSAHN WVPS
//
