ID A0A3B4G7Z2_9CICH Unreviewed; 2166 AA.
AC A0A3B4G7Z2;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=NBAS subunit of NRZ tethering complex {ECO:0000313|Ensembl:ENSPNYP00000018229.1};
OS Pundamilia nyererei.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Pundamilia.
OX NCBI_TaxID=303518 {ECO:0000313|Ensembl:ENSPNYP00000018229.1, ECO:0000313|Proteomes:UP000261460};
RN [1] {ECO:0000313|Ensembl:ENSPNYP00000018229.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR STRING; 303518.ENSPNYP00000018229; -.
DR Ensembl; ENSPNYT00000018682.1; ENSPNYP00000018229.1; ENSPNYG00000013714.1.
DR GeneTree; ENSGT00390000012474; -.
DR Proteomes; UP000261460; Unplaced.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.
DR GO; GO:0048703; P:embryonic viscerocranium morphogenesis; IEA:Ensembl.
DR GO; GO:2000623; P:negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:Ensembl.
DR GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:Ensembl.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; IEA:InterPro.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR029145; NBAS_N.
DR InterPro; IPR013244; Sec39_domain.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR15922:SF2; NBAS SUBUNIT OF NRZ TETHERING COMPLEX; 1.
DR PANTHER; PTHR15922; NEUROBLASTOMA-AMPLIFIED SEQUENCE; 1.
DR Pfam; PF15492; Nbas_N; 1.
DR Pfam; PF08314; Sec39; 2.
DR SMART; SM00320; WD40; 2.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 24..267
FT /note="Neuroblastoma-amplified sequence N-terminal"
FT /evidence="ECO:0000259|Pfam:PF15492"
FT DOMAIN 585..868
FT /note="Sec39"
FT /evidence="ECO:0000259|Pfam:PF08314"
FT DOMAIN 891..1133
FT /note="Sec39"
FT /evidence="ECO:0000259|Pfam:PF08314"
FT REGION 355..382
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1205..1227
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1755..1776
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 500..527
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 363..377
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1755..1772
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2166 AA; 243834 MW; 53619B5E8A084D06 CRC64;
RFSRLNRCYE SAVNESWETK ESELLRDPNP QWRRVAWSYD CTLLAYADST GTVRLFDLMG
SELFVIPPVA SFPGDFSCAV AGLIFLEYTA SAQWSAELLV ITYGGNLKSY LVSMGTNQNF
QENHSFSFSS HYSHGITSAI YHPGHRLLLV GGCESGDDSA SKASCCGITA WRALSGSPHY
KQVTSYEDDV SMNQKRGFFR IPSFRLFSRQ GDEKDGVFRM SLSPDGTLLA VIHFSGRLSL
WDIPSLKQRA TWSQDLQPGF EEINPEWKTS LERRKKIKDK EQFYPLVDVS WWSDNVLILA
RCSGSVTVSS VRTLRNLLGK SCEWFEPSPR VTAAHDGGFL SLECEVKLAQ KRGRLESSLS
GGASEDEEGD DGGESDSDEE SSAKARYFGY IKQGLYYVTE MERFAPPRKR PRTVIKNYRL
VSLRSTTPEE LYQRKSKIRK RSWVLHECVE RVPENVDAAK ELLQYGLKGT DLEALIAIGK
GEDGGRFIMP GDVDLDDLPY EDILSDEQEL EMKKERENKK RRELLAKVDF SRLTLEQKEL
CRSRLKLLSY LDRLATYEEI LGGPHAAEDK YDADFFKKFR SQNIVLSARN YARESNVQAL
DILFTYHGAE LLQHRLAILD NFPETTSPHE YTTLLPEACL DDRGELVLIP WDEQRHREMD
WCEAEECRAV LEQNLFDDDS FLYDEASDLL RFRTATPSKE LLTDWYISRA QDIDSCSRQV
DCALSLVRLG KEREIPGLER LCDDLVTMET LVYETSCELG LTLKDFQQLS DIDKLRLLMK
NSSTEHYVKD SFQWMVPFLH RCEGQKEGSA KSLLREYLVS LAQEDLTLPL IIFKHSKPDC
QQKIIGDPDQ LMEVALECIY SCERDDQLSL CYEILECLPQ RGYGSDTDIT PSLHDQVDKL
EKHLSVVEVL EKHGLQKPIS YVKNSQNNDE EAHQLMVKLC RHTGRKNPPV SENMWRVLLQ
DLLDMQQNVY TCLKPETCHQ VFVESLLCSS RVENIRLAGQ LMHCSKVSQD VPVSLSFRGK
GYALKVAYDN SVELVLAAAR EYFNSSKLLT DPCMGLARGC LQLITDCPPS IQEELDLINA
LSQLEDFNVS ILPLQVRLRS DRLSLVEECI AHCSTAYKQS TTLLNLASLL RVSGTCRHAC
TLTRYSPAWE VCSLLGQCDG YGDLEARQEL LAFSLTHCPP DSIHGLLAVL YQAVNYQMEP
VNTETGREVD ETDSLKPQPR VGSSVGTAGD LLHRTTAKTM EVLTTTGLNT KAVLTAVSDH
RWWKDSLNYL RPLHGRGSGA TSQEGACENA NLERQGCSPF YQDLIEDPYV DTSQDVYSFY
KEVPAENFAE VLLRTGKLAE AKTEGKTPFP ATEVLLQLAN DAFPRDMMLA LSYLLALPQV
LDANRCFDKQ CHSALSLQLA AYYYSLQIYS RLMPCFKDKN HTLYQADPKE LIRLVTQHVS
SYSDWPEELQ KLISQLHMYN ERLTDFTQAQ VLQGLGRGVD VQRFSSDADY KKETILGLTE
TLDDGVYRIA LSLAKRYSVP LWEVYMTHLE FLFTDSGLST KDIETRSESL SLFETLKCNP
QAFYSHMTKY VLPTVEGTDL NRLLYYYTLL DAAGCEPYVT TTIKPDSHVK LLKKLRAVAN
GLNYRKLTDE SSDPLATLQP VLTSQNVLSI SKLANRLPLP GGGGGATVSA SAVHAVWLQK
VFWKGDPQLL KRPPQSDQDY LHAYDTCAKY LDRLAPGDAV RFLDNITFSL DASKNLSIQA
RLEVIRRATK ALRQLGEKNR KRGGDDSREQ EGTDPAGMTF DEALAHLQQS QAHLDTLSHP
FILSLKDSQE QLRAYSQLYD LSRSERSKVC ELAVTMATDG QPLEQIGELL RVTVGSLDLS
LKSVLHDAVE RVVAALSGDP CALTNYPQPL RVLEAMVTAV HNSVQSGDST VTSDDLLAWL
RPFCGDASLP VRPRIDVLQI LESNFSLGDS DVRLLLLYRT QAVLRDREIQ IEDVENEEKR
YNKRPSYFHN PWVVLTSALL TRCKGSEVKT DLGQQVVTMV RSLYNSKHKL PVHIATLLLQ
NQPSLLQPAL KLMSESCDEQ LLQLTLDQIN GMSTVSTASS CDEELLSLLL DAGLLVGCVS
SALYPLLSSH MLSHQQEGGW DVEKAAAELM AAGHGPEAGS LLLAHRGTHP AQFTFNSALA
VLEKWL
//
