ID A0A3B4GHA1_9CICH Unreviewed; 1348 AA.
AC A0A3B4GHA1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Ras-associated and pleckstrin homology domains-containing protein 1-like {ECO:0000313|Ensembl:ENSPNYP00000021514.1};
OS Pundamilia nyererei.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Pundamilia.
OX NCBI_TaxID=303518 {ECO:0000313|Ensembl:ENSPNYP00000021514.1, ECO:0000313|Proteomes:UP000261460};
RN [1] {ECO:0000313|Ensembl:ENSPNYP00000021514.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR STRING; 303518.ENSPNYP00000021514; -.
DR Ensembl; ENSPNYT00000022032.1; ENSPNYP00000021514.1; ENSPNYG00000016134.1.
DR GeneTree; ENSGT00940000156552; -.
DR Proteomes; UP000261460; Unplaced.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01259; PH_APBB1IP; 1.
DR CDD; cd16136; RA_MRL_Lpd; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR039664; GRB/APBB1IP.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR039665; PH_APBB1IP.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR000159; RA_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR11243; GROWTH FACTOR RECEPTOR-BOUND PROTEIN; 1.
DR PANTHER; PTHR11243:SF15; RAS-ASSOCIATED AND PLECKSTRIN HOMOLOGY DOMAINS-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00788; RA; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00314; RA; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50200; RA; 1.
PE 4: Predicted;
FT DOMAIN 315..401
FT /note="Ras-associating"
FT /evidence="ECO:0000259|PROSITE:PS50200"
FT DOMAIN 442..551
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 102..264
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 581..615
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 631..718
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 768..1348
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7..21
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 102..258
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 637..657
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 658..685
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 686..713
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 774..793
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 804..846
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 868..930
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 934..992
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1018..1044
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1047..1099
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1100..1128
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1156..1183
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1193..1208
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1209..1229
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1230..1250
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1268..1283
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1308..1322
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1348 AA; 143724 MW; 02C58C5B81587EAA CRC64;
MDQVSDDELD HGAEEDSDKE DQDLDKMFGA WLGELDKLTQ SLDDGRPQKA LQKPPLRQET
NMANFSYRFS MYNINEALNQ GDTVDLDALM ADLCSIEQEL NTISKPNSTS RSQSKGQQRA
AGGRSASTKH TGTSGGGSSG GRSASSSTRA SPANTVRGGS ATARPAASNI SLDDITSQLE
KASLSMDEAA RQTSSSSSSS SSFSSSTIRR PSSGSSGGGG QHRRTGSVGA VTEQDAPSQR
SSVNSACASA SSMDSLDTDK VTGGEHSYLD QETSLILKSI AGKPSHLLTK EEQAAKLKAE
KIRVALEKIK EAQVKKLVIR VHMSDESSKT MMVDERQTVR QVLDSLLDKS HCGYSPDWSL
VETITELQME RIFEDHENLV ENLLNWTRDS HNKLMFIERI EKYALFKNPQ NYLLGRKETS
EMADRNKEAL LEECFCGGSV SVPEIEGILW LKEDGKKSWK KRYFLLRASG IYYVPKGKAK
ASRDLVCFLQ LDHVNVYYGQ DYRSKYKAPT DYCLALKHPQ IQKKSQYIKY LCCDDVRTLH
QWVNGIRIAK YGKQLYLNYQ EAMKRTEAAY DWSSLSTSSI RSGSSSASIP ESQSNHSGHS
DSGVDTGSSH GRSQSVVSSI FSEAWKRGTQ IEENSKEAVP PPPPQAAPPP PPLQPPQSAQ
LHQQQLQKQQ QSQAFSNYNH MPPQEQQQPA PAPPPPPPPP PPPPPPPPPV QTVSYQSPAL
TMYKYSTITR LQNQKGGKIP FHLPATAQQV LPTTLTPPAL QAIKPNVNHI AARTNVPPPP
PPPPPPPPSM PTPGSAMAVL KLGPPSPATP PAFIPPPPVP LPAPQTNGIA FPPPPPPPPP
PAIAAAPVSQ PVYHSGLKQA LKERFPSPPR DLPSPNGGLE YSPPPAPTPP PPPPPPPPPP
PPPPPPQQFQ VPAHCPTPAP PPPPPLPAPL KKQFSLQTGH TSTQPPPTLP KQHSLSKPPT
ISTGAPPTMS LVKQLASQFP GASSQAGNQM EASKAPLSPP AVKTKPKWQR GGGQQLQSPE
FPPPPPDTPV TGPTPPPPPL PSGNMGSPIR RSPSGSSSFG GKKPPPTPQR NSSIKSNASN
SYEESRRNLL SKFAPQGNTA PPSSCPPSNG SPSKEPSNGP PAPPKPGKLN LANLPLALQA
KVSQAKQSGG DFPSPPPECA YFPPPPPASE LFPPPPPPGN DAHTGGPPRV AVVNPQPQAP
PPPPPISLVS NSTWGKSSLK KTPPPTLGRR SNNTPEPPPL SPPPPTSPKG SSGQPNFLED
LNRTLRRKSV GRQGSTNSAG LSGKLDPAGT MDDMALPPPP PELLLDQGKQ SNGGNGGYMS
GNISGYATLR RGPPPAPPKR GDGTKLTG
//
