ID   A0A3B4GN87_9CICH        Unreviewed;       524 AA.
AC   A0A3B4GN87;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=Glycerate kinase {ECO:0000256|ARBA:ARBA00020720};
DE            EC=2.7.1.31 {ECO:0000256|ARBA:ARBA00012101};
GN   Name=glyctk {ECO:0000313|RefSeq:XP_005724639.1,
GN   ECO:0000313|RefSeq:XP_005724640.1, ECO:0000313|RefSeq:XP_005724642.1,
GN   ECO:0000313|RefSeq:XP_005724643.1, ECO:0000313|RefSeq:XP_005724644.1,
GN   ECO:0000313|RefSeq:XP_013764065.1, ECO:0000313|RefSeq:XP_013764066.1};
OS   Pundamilia nyererei.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Pundamilia.
OX   NCBI_TaxID=303518 {ECO:0000313|Ensembl:ENSPNYP00000022821.1, ECO:0000313|Proteomes:UP000261460};
RN   [1] {ECO:0000313|Ensembl:ENSPNYP00000022821.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
RN   [2] {ECO:0000313|RefSeq:XP_005724639.1, ECO:0000313|RefSeq:XP_005724640.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(R)-glycerate + ATP = (2R)-3-phosphoglycerate + ADP + H(+);
CC         Xref=Rhea:RHEA:23516, ChEBI:CHEBI:15378, ChEBI:CHEBI:16659,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:58272, ChEBI:CHEBI:456216;
CC         EC=2.7.1.31; Evidence={ECO:0000256|ARBA:ARBA00000694};
CC   -!- SIMILARITY: Belongs to the glycerate kinase type-2 family.
CC       {ECO:0000256|ARBA:ARBA00005393}.
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DR   RefSeq; XP_005724639.1; XM_005724582.1.
DR   RefSeq; XP_005724640.1; XM_005724583.1.
DR   RefSeq; XP_005724642.1; XM_005724585.1.
DR   RefSeq; XP_005724643.1; XM_005724586.1.
DR   RefSeq; XP_005724644.1; XM_005724587.1.
DR   RefSeq; XP_013764065.1; XM_013908611.1.
DR   RefSeq; XP_013764066.1; XM_013908612.1.
DR   STRING; 303518.ENSPNYP00000022814; -.
DR   Ensembl; ENSPNYT00000023376.1; ENSPNYP00000022814.1; ENSPNYG00000017232.1.
DR   Ensembl; ENSPNYT00000023382.1; ENSPNYP00000022821.1; ENSPNYG00000017232.1.
DR   GeneID; 102203390; -.
DR   CTD; 132158; -.
DR   GeneTree; ENSGT00390000014365; -.
DR   OrthoDB; 5404098at2759; -.
DR   Proteomes; UP000261460; Unplaced.
DR   Proteomes; UP000695023; Unplaced.
DR   GO; GO:0008887; F:glycerate kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.10180; Glycerate kinase, MOFRL-like N-terminal domain; 1.
DR   Gene3D; 3.40.1480.10; MOFRL domain; 1.
DR   InterPro; IPR037035; GK-like_C_sf.
DR   InterPro; IPR038614; GK_N_sf.
DR   InterPro; IPR007835; MOFRL.
DR   InterPro; IPR025286; MOFRL_assoc_dom.
DR   InterPro; IPR039760; MOFRL_protein.
DR   PANTHER; PTHR12227; GLYCERATE KINASE; 1.
DR   PANTHER; PTHR12227:SF0; GLYCERATE KINASE; 1.
DR   Pfam; PF13660; DUF4147; 1.
DR   Pfam; PF05161; MOFRL; 1.
DR   SUPFAM; SSF82544; GckA/TtuD-like; 1.
PE   3: Inferred from homology;
KW   Kinase {ECO:0000313|RefSeq:XP_005724639.1,
KW   ECO:0000313|RefSeq:XP_005724640.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000695023};
KW   Transferase {ECO:0000313|RefSeq:XP_005724639.1,
KW   ECO:0000313|RefSeq:XP_005724640.1}.
FT   DOMAIN          33..281
FT                   /note="MOFRL-associated"
FT                   /evidence="ECO:0000259|Pfam:PF13660"
FT   DOMAIN          399..510
FT                   /note="MOFRL"
FT                   /evidence="ECO:0000259|Pfam:PF05161"
SQ   SEQUENCE   524 AA;  56358 MW;  123C31AAB1F30CC5 CRC64;
     MARVLSLFRS QPFLHLVARR KPTFCKMSMD TRAREVFAAA VEAVQPDTVV CQSIERKEDS
     VVIDGRTFTL KHNLHLVGFG KAVLGMAAEA ERIVGDHLVK GVISVPHGIQ QTLQQHGKDH
     LLLKENSRIK VIEGAKHNLP DPDAQKAAEE IKHLVSELTE KDLLLVLISG GGSALLPAPI
     PPITLQEKLD VTCRLAGAGA TIQELNTIRR ALSLLKGGGL AHHAHPAQVV ALILSDVIGD
     PIDMIASGPT VMSRVWPEEV LSILERYKLL NLLPTSVKEV LDKPNSRWKE NKEESDTSGH
     VLNAVIGSNG VALKHAGLRA RELGFLPVVL SPSVCGDVRS VSRLYGLLAR FACSREEPPP
     DIATEVLKLG PEVGVESWDL CRTMQVLEKG RTEGWGATCL LAGGEPTVEL TGKGRGGRNQ
     ELAMRVGLEL RSLGLSPKGP VFLSGGTDGQ DGPTEAAGAI TDGGLYDEAK AQGLDIDNFL
     INNDSYTFFS RLSGGQQLLV PGLTCTNVMD VHMLLIPAIP IIIR
//