ID   A0A3B4GUN1_9CICH        Unreviewed;       656 AA.
AC   A0A3B4GUN1;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   RecName: Full=NACHT domain-containing protein {ECO:0000259|PROSITE:PS50837};
OS   Pundamilia nyererei.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Pundamilia.
OX   NCBI_TaxID=303518 {ECO:0000313|Ensembl:ENSPNYP00000025128.1, ECO:0000313|Proteomes:UP000261460};
RN   [1] {ECO:0000313|Ensembl:ENSPNYP00000025128.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B4GUN1; -.
DR   STRING; 303518.ENSPNYP00000025128; -.
DR   Ensembl; ENSPNYT00000025744.1; ENSPNYP00000025128.1; ENSPNYG00000018974.1.
DR   GeneTree; ENSGT01100000263513; -.
DR   Proteomes; UP000261460; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR029495; NACHT-assoc.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR041267; NLRP_HD2.
DR   InterPro; IPR041075; NOD2_WH.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR   PANTHER; PTHR24106:SF151; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12-RELATED; 1.
DR   Pfam; PF14484; FISNA; 1.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF17776; NLRC4_HD2; 1.
DR   Pfam; PF17779; NOD2_WH; 1.
DR   SMART; SM01288; FISNA; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
FT   DOMAIN          141..275
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
FT   REGION          62..121
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        99..121
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   656 AA;  74825 MW;  FA0774F8137D5A02 CRC64;
     MYNYFYIYSI YNHLHAALGR KVDCQCVQHG SDVWLHDFSL IGSFVKYSVP AAGGTHHHIC
     EERAEEDREG SESSIPRIGI CEDHSGLPEE NEAGGAGTAE VNDEHEVRQI ETASRKPDRP
     ETTIRKEDIF KASPGRDEPI RTVLTKGVAG IGKTVLTQKY SLDWAEDKAN QDIQFIFPFT
     FRELNVLKEE KFSLVELVHH FFIETKEAGI CSFEDFQVVF IFDGLDECRL PLDFHKTIIL
     TDPRKSTSVD VLLINLIRGK LLPSAHLWIT TRPAAANQIP PDCVDRVTEV RGFNEPQKEE
     YFRKRFRDEE QASRIIFHIK TSRSLHIMCH IPVFCWITAT VLEDELKTSD SEDLPKTLTE
     LYIHFVLFYL KTKDIKYDGG AETDSCWNPE NKKMIESLGK LAFDQLQKGN LIFYESDLTE
     CGIDIRAASV YSGVFTQVFK EERGLYQDKV FCFIHLSVQE FLSALHVHLT FINSGVNLLE
     QQTTAKLLLL FRKQESREAE SSEKIFYECA VDKALHSPNG HLDLFLRFLL GLSLQTNQTL
     LRGLLTQTGS ISQTHQETIQ YIKKKLSEDL SAEKSINLLH CLNELDDRSL VDEMQQSLRS
     GNLSADKLSP AQWSALTFIL LSLEKDLDVF DLKKYSASEE ALLRLLPVVK ASNKAR
//