ID   A0A3B4GW51_9CICH        Unreviewed;       467 AA.
AC   A0A3B4GW51;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Phosphatidylinositol 3-kinase regulatory subunit gamma-like {ECO:0000313|Ensembl:ENSPNYP00000027220.1, ECO:0000313|RefSeq:XP_005741954.1};
GN   Name=LOC102198353 {ECO:0000313|RefSeq:XP_005741954.1};
OS   Pundamilia nyererei.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Pundamilia.
OX   NCBI_TaxID=303518 {ECO:0000313|Ensembl:ENSPNYP00000027220.1, ECO:0000313|Proteomes:UP000261460};
RN   [1] {ECO:0000313|Ensembl:ENSPNYP00000027220.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
RN   [2] {ECO:0000313|RefSeq:XP_005741954.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_005741954.1; XM_005741897.1.
DR   AlphaFoldDB; A0A3B4GW51; -.
DR   STRING; 303518.ENSPNYP00000027220; -.
DR   Ensembl; ENSPNYT00000027884.1; ENSPNYP00000027220.1; ENSPNYG00000020525.1.
DR   GeneID; 102198353; -.
DR   GeneTree; ENSGT00940000156259; -.
DR   OrthoDB; 2880119at2759; -.
DR   Proteomes; UP000261460; Unplaced.
DR   Proteomes; UP000695023; Unplaced.
DR   CDD; cd09942; SH2_nSH2_p85_like; 1.
DR   Gene3D; 1.10.287.1490; -; 1.
DR   Gene3D; 3.30.505.10; SH2 domain; 2.
DR   InterPro; IPR032498; PI3K_P85_iSH2.
DR   InterPro; IPR035022; PI3kinase_P85_nSH2.
DR   InterPro; IPR000980; SH2.
DR   InterPro; IPR036860; SH2_dom_sf.
DR   PANTHER; PTHR10155; PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT; 1.
DR   PANTHER; PTHR10155:SF10; PI3K21B, ISOFORM B; 1.
DR   Pfam; PF16454; PI3K_P85_iSH2; 1.
DR   Pfam; PF00017; SH2; 2.
DR   PRINTS; PR00678; PI3KINASEP85.
DR   PRINTS; PR00401; SH2DOMAIN.
DR   SMART; SM00252; SH2; 2.
DR   SUPFAM; SSF55550; SH2 domain; 2.
DR   PROSITE; PS50001; SH2; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000695023};
KW   SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191}.
FT   DOMAIN          48..143
FT                   /note="SH2"
FT                   /evidence="ECO:0000259|PROSITE:PS50001"
FT   DOMAIN          338..432
FT                   /note="SH2"
FT                   /evidence="ECO:0000259|PROSITE:PS50001"
FT   REGION          17..39
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          434..467
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        25..39
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   467 AA;  54359 MW;  1C23E07EB503FBA7 CRC64;
     MIYPPEGLFY IEMDQAPALP PRSTKPPSST MNSNCLSPPA HSLQDAEWYW GDITREEVNE
     KLRDTPDGSF LVRDASTKQQ GDFTLTLRKD GHNKLIKIYH RDGKYGFSDP LTFTSVVELI
     WYYEHHPLVE YNASLDLMLT HPVSRFQQVK EDSVDVTGRK LKEVHSQYQE KSKEFDRLYE
     AFTKTSQEIQ MKRTAIEAFN ETMMIFEEQC REQERYGEEF ERSSHLEGID KDLESFLIHY
     EKLKCRLAEI YDSKIHLEED LRTQVEDYRE TDRKINNLRP DLIQLRIMRD QYLNWLNHKG
     VRQKRINDWL GAHNDSLDDT YVLKGDEKNL PHQDETSWFV GELSRTQAEE MLQGKVPGTF
     LIRESSKQGC YACSVVVNEE VKHCMIYSTP HGYGFAEPYD VHCSLKDLVL HYRLHSLVQH
     NDALDVRLSH PVHAKAAATP SQHAEEQHKL IQTPKHTSGM APAAPEM
//