ID   A0A3B4GXP2_9CICH        Unreviewed;       417 AA.
AC   A0A3B4GXP2;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   SubName: Full=Protein arginine methyltransferase 2 {ECO:0000313|Ensembl:ENSPNYP00000026031.1};
OS   Pundamilia nyererei.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Pundamilia.
OX   NCBI_TaxID=303518 {ECO:0000313|Ensembl:ENSPNYP00000026031.1, ECO:0000313|Proteomes:UP000261460};
RN   [1] {ECO:0000313|Ensembl:ENSPNYP00000026031.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B4GXP2; -.
DR   STRING; 303518.ENSPNYP00000026031; -.
DR   Ensembl; ENSPNYT00000026668.1; ENSPNYP00000026031.1; ENSPNYG00000019621.1.
DR   GeneTree; ENSGT00940000160683; -.
DR   Proteomes; UP000261460; Unplaced.
DR   GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR   GO; GO:0016274; F:protein-arginine N-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 2.70.160.11; Hnrnp arginine n-methyltransferase1; 1.
DR   Gene3D; 2.30.30.40; SH3 Domains; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR025799; Arg_MeTrfase.
DR   InterPro; IPR041698; Methyltransf_25.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   PANTHER; PTHR11006; PROTEIN ARGININE N-METHYLTRANSFERASE; 1.
DR   PANTHER; PTHR11006:SF92; PROTEIN ARGININE N-METHYLTRANSFERASE 2; 1.
DR   Pfam; PF13649; Methyltransf_25; 1.
DR   Pfam; PF00018; SH3_1; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   SUPFAM; SSF50044; SH3-domain; 1.
DR   PROSITE; PS51678; SAM_MT_PRMT; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000256|PROSITE-ProRule:PRU01015};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW   ECO:0000256|PROSITE-ProRule:PRU01015};
KW   SH3 domain {ECO:0000256|ARBA:ARBA00022443};
KW   Transferase {ECO:0000256|PROSITE-ProRule:PRU01015}.
FT   DOMAIN          26..59
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|Pfam:PF00018"
FT   DOMAIN          124..221
FT                   /note="Methyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF13649"
SQ   SEQUENCE   417 AA;  47057 MW;  5D28428C6DDC2905 CRC64;
     MTPEERRKCN CGGISNNRVT FFLVSQLSFS RGDRLLVHAK PSSEWWWAEL QGVIGYVPAS
     YMSQDAAGEE EEDPSIEDPW QDEEYFGNYG TLRLHLEMLS DKSRTEAYRQ VILSNSASLS
     SKRVMDLGCG TGIISLFCAQ LARPSMVYAV EASSMAEYTR QLVKQNGYDE VVTVLQGRAE
     EIELPEQVDV LVSEWMGNCL LFEFMVESVL LARDRWLRNG GTMWPSSAAL TFVPCQADSY
     YAEKMAFWER PYGLDFTPLQ PLAQQEFFTK PKFSHIIEPC DCLAAPCDVI SFDMYTLQVG
     DLEEMKGQFH FCVEKSGVFH GFTAWFTVCF ESLEAGGATV ELNTGPNSGP THWKQTLFML
     DRPVSVCAGD SISGTIVLQR NPVWRRHMTV TLHWTIKGST DNPDNSQAGT KSFPMWR
//