ID A0A3B4GYB2_9CICH Unreviewed; 482 AA.
AC A0A3B4GYB2;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Limb development membrane protein 1 like {ECO:0000313|Ensembl:ENSPNYP00000026271.1};
OS Pundamilia nyererei.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Pundamilia.
OX NCBI_TaxID=303518 {ECO:0000313|Ensembl:ENSPNYP00000026271.1, ECO:0000313|Proteomes:UP000261460};
RN [1] {ECO:0000313|Ensembl:ENSPNYP00000026271.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004477}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004477}.
CC -!- SIMILARITY: Belongs to the LIMR family.
CC {ECO:0000256|ARBA:ARBA00010487}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3B4GYB2; -.
DR Ensembl; ENSPNYT00000026912.1; ENSPNYP00000026271.1; ENSPNYG00000019782.1.
DR GeneTree; ENSGT00390000007809; -.
DR Proteomes; UP000261460; Unplaced.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR InterPro; IPR008075; LIMR.
DR InterPro; IPR006876; LMBR1-like_membr_prot.
DR PANTHER; PTHR12625; LIPOCALIN-1 INTERACTING MEMBRANE RECEPTOR LIMR; 1.
DR PANTHER; PTHR12625:SF2; PROTEIN LMBR1L; 1.
DR Pfam; PF04791; LMBR1; 2.
DR PRINTS; PR01692; LIPOCALINIMR.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Endocytosis {ECO:0000256|ARBA:ARBA00022583};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687}.
FT TRANSMEM 15..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 50..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 95..121
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 142..162
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 182..203
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 284..309
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 329..359
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 379..396
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 416..439
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 482 AA; 54099 MW; 20571EE756022706 CRC64;
MPVLRPLNAK ITLEFSLFLL QICVLLFTCL YMLSYLILNQ FRKTAEFVTG ELWLCTFTLS
VAVCAVLLLP ISILSNEVLL TFPQSYYMQW LNGSLIHGLW NLVFLFSNLS LVFLMPFAYF
FTESEGFAGS RKGVMARVYE AVVLLLLLAL LVLGIVWVAS ALLHDNIARK SLYDLWEYYL
PYLYSGISLF GVLLLLLCTP LGLSRMFSVT GSLLVKPRLL EDVEDTLSCT TFEEDSLSRK
INCGSTSCWV KLNMEALKKE YQAVQSKRVA LEMRRKASPW QRNLGYPLAM LVLLALTVMC
VLMVCFNVLE LLLDETAMPR GMEDPHLGMA SFSMFGSLGA AVQVVLILYL MVSSVVGFYS
SPLFTGLLPR AQDTNLTQII ANCVSLLILS SALPVFSRTL GITRFDLLGD FGRYNWLGNF
YVVFLYNMLF AGLTSASLIK TVTWAVQREL IRAFGLHRLP LTVSRSTVPF RLLLASGLSK
IQ
//
