ID A0A3B4GYI9_9CICH Unreviewed; 1254 AA.
AC A0A3B4GYI9;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Protocadherin 7 {ECO:0000313|Ensembl:ENSPNYP00000028000.1};
GN Name=PCDH7 {ECO:0000313|Ensembl:ENSPNYP00000028000.1};
OS Pundamilia nyererei.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Pundamilia.
OX NCBI_TaxID=303518 {ECO:0000313|Ensembl:ENSPNYP00000028000.1, ECO:0000313|Proteomes:UP000261460};
RN [1] {ECO:0000313|Ensembl:ENSPNYP00000028000.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B4GYI9; -.
DR STRING; 303518.ENSPNYP00000028000; -.
DR Ensembl; ENSPNYT00000028685.1; ENSPNYP00000028000.1; ENSPNYG00000021073.1.
DR GeneTree; ENSGT00940000157221; -.
DR Proteomes; UP000261460; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 7.
DR Gene3D; 2.60.40.60; Cadherins; 7.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR020894; Cadherin_CS.
DR InterPro; IPR013164; Cadherin_N.
DR InterPro; IPR013585; Protocadherin.
DR PANTHER; PTHR24028; CADHERIN-87A; 1.
DR PANTHER; PTHR24028:SF253; PROTOCADHERIN-7; 1.
DR Pfam; PF00028; Cadherin; 5.
DR Pfam; PF08266; Cadherin_2; 1.
DR Pfam; PF08374; Protocadherin; 1.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 7.
DR SUPFAM; SSF49313; Cadherin-like; 7.
DR PROSITE; PS00232; CADHERIN_1; 4.
DR PROSITE; PS50268; CADHERIN_2; 7.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043}; Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Membrane {ECO:0000256|SAM:Phobius}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 845..868
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 47..138
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 139..275
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 276..382
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 399..502
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 503..606
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 607..709
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 720..816
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT REGION 876..988
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1035..1167
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1206..1248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 876..898
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 966..984
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1035..1069
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1133..1167
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1254 AA; 137133 MW; 67DA250BB29B14CB CRC64;
MRTTGAVDYL YYCMLILQLV HQPAAKQVLR YRLAEEGPAD VRVGNVATDL GIVAGSGEVT
FTLESGSDFF KIDNITGELS TNERRIDREK LQQCQMIFDE NECFIDFEVS VIGPAQSWVD
LFEGKVIILD INDNTPSFPS PVLTLSVEEN RPIGTLYLLP TATDRDFGRN GIERYELIQD
NGENSRRLGS SGDSFSGKRR FEEGASRSSV FELQVADTTD GEKQPQLIIK GALDREQRDS
YELTLRVRDG GDPPRSSQAI LRVMITDVND NSPRFEKSVY EADLPENSSP GAPILQLKAA
DADVGVNGQI EYVFGAATES VRRLLRLDES TGWLSVLHRI DREEVSQLRF SVMARDRGQP
PKMDKATVVL NIKDENDNVP AIEIRKIGRI FLKDGIANVA EDVVVDTPIA LVQVSDRDQG
ENGIVTCTVV GDVPFQLKPA SEMEGEQNKK KYFLHTSAQL DFEATQEYNV VIVAVDSGSP
SLASNNSLLV KVGDTNDNPP IFSQNVVEVS FPENNAPGER VTTVKAIDAD SGRNAEIAYS
LDSSVNGIFS IDADSGDIRV NTILDRELTE RYEFKVIAKD KGINTLQGSA TVVVLVADKN
DNEPKFMQDV FTFYVKENLD PNSPVGMVTV IDADKDQNAE MGLFIEEEED IFSIENETGT
IFSTLSFDRE QKGTYTFRVK AVDGGDPPKS ATATVSLFVM DENDNAPSVT FPINSSYTLL
PPSTNIRTVV RTVTASDADT GINAVLNFSI IGGNPFRLFE IDAERGVISL MAKLEQKHHG
LHRLVVQVND KGQPSQSTTT LVHVYVNETL SNSSAVEAQV AKSLSTSLNT NIAGDPNYDL
SKQRLSIVIG IVSGIMTVIL IILVVVMARY CRPKNKNGYE AGKKDHEDFF TPQQHDKSKK
PKKDKKKQKS KQPLYSSIVT VEASKPNGQR YDGVNEKLSD SPGMGRYRSV NGGPGSPDLA
RHYKSSSPLP TVQLHPQSPT AGKKHQAVQD LPPANTFVGT GDNISLGSDH CSEYSSQTIN
KYNKQPFRRV TFSVVSQPQD PHQQGSLQSC YDSGLDESET PSSKSSSGPR LGALPLPEDS
YERTTPDGSV GEAEHMENSR PLPDVAMTGK CTRECDEYGH SDSCWMPVRT SPERRPSKST
TTPQQPKLST FMSGNGSGSS SAEQPGSQET LAMAAMANGD PTAAHMMGDR NRNLLNKKMA
SSSSSYEAFG SPPYGSPGAG EEVLGHPTEE IPLAPTGEYK PTTCGTLTRR EVYL
//
