ID   A0A3B4H082_9CICH        Unreviewed;       271 AA.
AC   A0A3B4H082;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=IRG-type G domain-containing protein {ECO:0000259|PROSITE:PS51716};
OS   Pundamilia nyererei.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Pundamilia.
OX   NCBI_TaxID=303518 {ECO:0000313|Ensembl:ENSPNYP00000028585.1, ECO:0000313|Proteomes:UP000261460};
RN   [1] {ECO:0000313|Ensembl:ENSPNYP00000028585.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the TRAFAC class dynamin-like GTPase
CC       superfamily. IRG family. {ECO:0000256|ARBA:ARBA00005429}.
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DR   AlphaFoldDB; A0A3B4H082; -.
DR   Ensembl; ENSPNYT00000029282.1; ENSPNYP00000028585.1; ENSPNYG00000021508.1.
DR   GeneTree; ENSGT00950000183007; -.
DR   Proteomes; UP000261460; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0098542; P:defense response to other organism; IEA:UniProt.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR030385; G_IRG_dom.
DR   InterPro; IPR007743; Immunity-related_GTPase-like.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR32341; INTERFERON-INDUCIBLE GTPASE; 1.
DR   PANTHER; PTHR32341:SF10; INTERFERON-INDUCIBLE GTPASE 5; 1.
DR   Pfam; PF05049; IIGP; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51716; G_IRG; 1.
PE   3: Inferred from homology;
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          52..232
FT                   /note="IRG-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51716"
SQ   SEQUENCE   271 AA;  30884 MW;  74901B2B875F53F8 CRC64;
     MGNWLNDCSA HVWMTADNSD EKETKPVTNC KHNNTAAAAA KIEENIKQQN NIPLNIAITG
     ESGAGKSTFV NAFRGLCDDE EGAAPTGVTE TTSEATPYPH PKYPNVILWD LPGIGTTKFP
     AKKYLKLVGF EKFDFFIIIS TTRFTENDVK LAQEIQKMKK KFYFVRSKVD NDIRAERRNR
     HFSEERTLTK IRDDCVQRLG GLGFESPQVF LVSSFELHLY DFNLLHQTLD KDLPKNKRDA
     LLFVIVHVLW CSDYPYGKDI YKSYKVCVCL V
//