ID A0A3B4H3Z6_9CICH Unreviewed; 1696 AA.
AC A0A3B4H3Z6;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Bromodomain and WD repeat domain containing 3 {ECO:0000313|Ensembl:ENSPNYP00000028298.1};
GN Name=BRWD3 {ECO:0000313|Ensembl:ENSPNYP00000028298.1};
OS Pundamilia nyererei.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Pundamilia.
OX NCBI_TaxID=303518 {ECO:0000313|Ensembl:ENSPNYP00000028298.1, ECO:0000313|Proteomes:UP000261460};
RN [1] {ECO:0000313|Ensembl:ENSPNYP00000028298.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR STRING; 303518.ENSPNYP00000028298; -.
DR Ensembl; ENSPNYT00000028989.1; ENSPNYP00000028298.1; ENSPNYG00000021206.1.
DR GeneTree; ENSGT00950000183107; -.
DR Proteomes; UP000261460; Unplaced.
DR CDD; cd05529; Bromo_WDR9_I_like; 1.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 2.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR16266:SF25; BROMODOMAIN AND WD REPEAT-CONTAINING PROTEIN 3; 1.
DR PANTHER; PTHR16266; WD REPEAT DOMAIN 9; 1.
DR Pfam; PF00439; Bromodomain; 2.
DR Pfam; PF00400; WD40; 5.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 2.
DR SMART; SM00320; WD40; 8.
DR SUPFAM; SSF47370; Bromodomain; 2.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00633; BROMODOMAIN_1; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 2.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 5.
DR PROSITE; PS50294; WD_REPEATS_REGION; 4.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|ARBA:ARBA00023117, ECO:0000256|PROSITE-
KW ProRule:PRU00035}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 150..191
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 192..233
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 234..270
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 332..365
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 434..476
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 1138..1208
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 1288..1358
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 645..665
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 764..899
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1421..1696
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 770..794
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 810..835
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1421..1494
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1495..1509
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1527..1556
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1557..1613
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1617..1641
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1649..1666
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1696 AA; 191145 MW; B8440B19FC169CA0 CRC64;
ARFLQSGPCK KAAKLVPQRW SWDGKKYKRN FQDWVVLNQH IPADYLLRIC QRIGPLIEKE
IPPCVPGVQT LLGLGRQSLL RTSKSCSHKV CSGSAVAALH RGRPPEPPVS NGSSPNVVSI
MGARQATGTG RFGQVLPSSS YQHMKIHKRI LGHLSSVYCV AFDRTGRRIF TGSDDCLVKI
WATDDGRLLA TLRGHSAEIC DMAVNHENSL IASASCDKVI RVWCLRTCAP ITVLQAHAAS
ITSIQFCPAA RGTTRYLAST GADGMVCFWK WHSLTMKFND HPVKFMERSR PGVQVSTSSF
SSGGMFMATG GTDHMIRVYY LGAESPMKVS EMDAHTDKVV VVQFSNNSDS LRFVSGSRDG
TVKIWHYQQQ EWKSITLDMA ARLPGSTAAT GDDKAKLVVT MVAWDRTDST IITAVSNYLL
KVWSTSTGQL LHILSGHDDE VFVLEAHPFD SRIMLSAGHD GNIYIWDLTK GVKIRNFFNM
IEGQGHGAIF DCKFSADGQH FACTDSHGHL LIFGFGCSRP YEKWICDYTF CSLIIRIGIP
DQMFFHTDYR PLIRDSNNYV LDEQTQQAPH LMPPPFLVDV DGNPHPPHYQ RLVPGRENCK
EEQLIPQMGY MANNDGELVE QVLGQQTAEN GESPLDNLIR QLQNEQDERQ NAEQEAEGEE
GAVPSSPVVA LRRSGQVDGV WQMQHNALPS QVATERDLLA WSRRVVVNEV LQGIFRVSEE
CRQAKGDIEC SLYYTERKKK PVTCAPKVRY FLRHYCYKTH KRHAYQTRSA QIRRPGTRSR
NPSNRRTSNS QMDSESDGEA EEQVEQTDPS SDGDARWQSE SSSSDSSSEY SDWTADAGIN
LQPPKRPTRR PVQPPDYSSS EEEGDNEAKE ARTREKEKRK KKSKETKQKP TSSLGGLDAE
EWLPPSWIME TVPRRSPFVP QMGDELIYFK QGHQAYVRAV RRAKAYSINP QKQPWNRLNL
RDQESVKVVG IKYEVGPPTL CCLKVAFLDP VSGKMTNESF SLKYHDMPDV IDFLVLQQFY
NEAKEHNWQP GMRFRSIIDD AWWFGSVEDQ EPLQPEYPDS LFQCYAVKWD NGEREKMSPW
DMEPIPEEAA LPEQVGDGVE VAEEELKALL YEPQEGEWGA HTRDEECERV IHGIDQLLTL
DVAKAFALPV NLQDYPLYCT VVAYPTDLSS IRTRLENRFY RRISALMWEV RYIEHNARTF
NEPQSPIVAA AKVVTDVLLH YIGDQSCIDV LDLYRKLKSE VSSEAEVGVD LDVDSDTPGT
STGHRKRGVV LDPKAWRGQC RELLRRMTAS TNSEPFRQPV DLFEYPDYRD IIDTPMDLGT
VSETLAVGNY ENPMEFSKDI RLIFSNSKAY TPNKKSQIYT MTLSLSAFFE KHIISIISDY
KSAIQNERRA RQHLTYRNRL HNGGSSPPNS PSHRYSATFT NLDEEDVQPS SPTSGTSVRS
RNQGPHRVTR SQATPVKKSG IASRSNSSSL ESSSTSSSSS SSSSSSSSSS DSDNSSDSEV
EKYVEGGGDH DYSKAPCLSV RLSAKGKVAA SEKRRHKGGE DTEAQGPKRA RLQLEVEEQE
DDEEEEEEEE AEEDEEEEEE EEEEKEQQQQ EEEEEEEEEE EEEEEEPEDE DDNNSEVQTR
AAAAPAAASS QRGSQCKSRR VNTRNQGRRT VRYGDDSEDD GHGSKDDPLN LGMSRSGRVR
RMTEKARVSH LMGWSH
//
