ID A0A3B4H663_9CICH Unreviewed; 573 AA.
AC A0A3B4H663;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Thyroid receptor-interacting protein 6-like {ECO:0000313|Ensembl:ENSPNYP00000029919.1, ECO:0000313|RefSeq:XP_013770969.1};
GN Name=LOC102194707 {ECO:0000313|RefSeq:XP_013770969.1};
OS Pundamilia nyererei.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Pundamilia.
OX NCBI_TaxID=303518 {ECO:0000313|Ensembl:ENSPNYP00000029919.1, ECO:0000313|Proteomes:UP000261460};
RN [1] {ECO:0000313|Ensembl:ENSPNYP00000029919.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_013770969.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_013770969.1; XM_013915515.1.
DR AlphaFoldDB; A0A3B4H663; -.
DR STRING; 303518.ENSPNYP00000029919; -.
DR Ensembl; ENSPNYT00000030650.1; ENSPNYP00000029919.1; ENSPNYG00000022560.1.
DR GeneID; 102194707; -.
DR CTD; 7205; -.
DR GeneTree; ENSGT00940000156022; -.
DR OrthoDB; 370973at2759; -.
DR Proteomes; UP000261460; Unplaced.
DR Proteomes; UP000695023; Unplaced.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd09350; LIM1_TRIP6; 1.
DR CDD; cd09357; LIM3_Zyxin_like; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 3.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR24212:SF7; THYROID RECEPTOR-INTERACTING PROTEIN 6; 1.
DR PANTHER; PTHR24212; ZYXIN/TRIP6; 1.
DR Pfam; PF00412; LIM; 3.
DR SMART; SM00132; LIM; 3.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 3.
DR PROSITE; PS50023; LIM_DOMAIN_2; 3.
PE 4: Predicted;
KW LIM domain {ECO:0000256|ARBA:ARBA00023038, ECO:0000256|PROSITE-
KW ProRule:PRU00125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00125}; Receptor {ECO:0000313|RefSeq:XP_013770969.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000695023};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 374..432
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 434..494
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 495..564
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT REGION 1..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 161..352
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 86..115
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 196..215
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 223..258
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 307..345
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 573 AA; 62910 MW; A15E9F46C03EC036 CRC64;
MSGPTWLPPR TLDSPERATP QMSHSAGGAI YRAPMKKGTP DFRPKYGPYD QNGGGGGGGG
MANRYMATGP TGGPMHHSSG DHYYPSPHGP KEDRSWSPHM DSYEMMHRGP EKPANYHSKI
DAEIDSLTSM LADLDSHPQD SSTQLYDNVP YNKYLSADHY KPAHQSAAPP QGRPSMSYNP
HPQSQYHPAP PYPNEHQTPQ YSTSHQQDYY TTSTPKPYPQ PVPASYTTAS TPTGPRFSVQ
VKTAQPVTYS QTGRQAEQAY TPPPPRQHVS RPPPQTQTAP QGWYPPHPGS QVQEMHSEGG
YKGSGSGSGG RVNQLPVSKR AMENNQSGSG AAQGPGYQSS KQGAATPRPE EELDRLTKKL
VYDMNHPPAE DYFGRCARCG DNVVGDGSGC IAMEQVFHVE CFTCITCHAR LRGQPFYALD
KKSYCESCYI STLERCSKCS KPILDRILRA MGKAYHPRCF TCVICNCCLD GVPFTVDATS
QIHCIEDFHR KYAPRCSVCG EPIMPEPGQE ETVRIVALDR SFHVNCYVCE ECGLLLSSEG
DGRGCYPLDG HILCKSCSAR RIQDLSAKIS TDC
//
