ID A0A3B4H7M0_9CICH Unreviewed; 178 AA.
AC A0A3B4H7M0;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=small monomeric GTPase {ECO:0000256|ARBA:ARBA00011984};
DE EC=3.6.5.2 {ECO:0000256|ARBA:ARBA00011984};
OS Pundamilia nyererei.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Pundamilia.
OX NCBI_TaxID=303518 {ECO:0000313|Ensembl:ENSPNYP00000031857.1, ECO:0000313|Proteomes:UP000261460};
RN [1] {ECO:0000313|Ensembl:ENSPNYP00000031857.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189; EC=3.6.5.2;
CC Evidence={ECO:0000256|ARBA:ARBA00023421};
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Ras family.
CC {ECO:0000256|ARBA:ARBA00008344}.
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DR AlphaFoldDB; A0A3B4H7M0; -.
DR Ensembl; ENSPNYT00000032619.1; ENSPNYP00000031857.1; ENSPNYG00000024035.1.
DR GeneTree; ENSGT00940000160167; -.
DR Proteomes; UP000261460; Unplaced.
DR GO; GO:0003925; F:G protein activity; IEA:UniProtKB-EC.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001806; Small_GTPase.
DR PANTHER; PTHR45704:SF18; PROTEIN CBG04185; 1.
DR PANTHER; PTHR45704; RAS-LIKE FAMILY MEMBER 11; 1.
DR Pfam; PF00071; Ras; 1.
DR SMART; SM00175; RAB; 1.
DR SMART; SM00173; RAS; 1.
DR SMART; SM00174; RHO; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51419; RAB; 1.
DR PROSITE; PS51421; RAS; 1.
PE 3: Inferred from homology;
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
SQ SEQUENCE 178 AA; 20032 MW; 641E466CC309A3E4 CRC64;
MHFPFCPVNS ERYLSWANVF LVVYSIDNME SFNGCQLYLQ TLASHNKTFR PQTPIILLGN
KKDMDRYRQV RQSDGEALAS HFGCVFFEVS ACQDFHSVQQ VFHEAVRRAR KGGACGCLVP
AIYASEDKAL LGVPSFTTPC YKELPVPANA KLITVKTSRA QSKRRASTLT LLKGFKIF
//
