ID   A0A3B4H9S0_9CICH        Unreviewed;       753 AA.
AC   A0A3B4H9S0;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=Double-stranded RNA-specific editase B2-like {ECO:0000313|Ensembl:ENSPNYP00000032060.1};
GN   Name=ADARB2 {ECO:0000313|Ensembl:ENSPNYP00000032060.1};
OS   Pundamilia nyererei.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Pundamilia.
OX   NCBI_TaxID=303518 {ECO:0000313|Ensembl:ENSPNYP00000032060.1, ECO:0000313|Proteomes:UP000261460};
RN   [1] {ECO:0000313|Ensembl:ENSPNYP00000032060.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B4H9S0; -.
DR   STRING; 303518.ENSPNYP00000032060; -.
DR   Ensembl; ENSPNYT00000032829.1; ENSPNYP00000032060.1; ENSPNYG00000024203.1.
DR   GeneTree; ENSGT00940000157252; -.
DR   Proteomes; UP000261460; Unplaced.
DR   GO; GO:0004000; F:adenosine deaminase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   CDD; cd19896; DSRM_RED2_rpt1; 1.
DR   CDD; cd19899; DSRM_RED2_rpt2; 1.
DR   Gene3D; 3.30.160.20; -; 2.
DR   InterPro; IPR002466; A_deamin.
DR   InterPro; IPR044460; ADAR3_DSRM_1.
DR   InterPro; IPR014720; dsRBD_dom.
DR   PANTHER; PTHR10910:SF17; DOUBLE-STRANDED RNA-SPECIFIC EDITASE B2; 1.
DR   PANTHER; PTHR10910; EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN; 1.
DR   Pfam; PF02137; A_deamin; 1.
DR   Pfam; PF00035; dsrm; 2.
DR   SMART; SM00552; ADEAMc; 1.
DR   SMART; SM00358; DSRM; 2.
DR   SUPFAM; SSF54768; dsRNA-binding domain-like; 2.
DR   PROSITE; PS50141; A_DEAMIN_EDITASE; 1.
DR   PROSITE; PS50137; DS_RBD; 2.
PE   4: Predicted;
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00266}.
FT   DOMAIN          132..198
FT                   /note="DRBM"
FT                   /evidence="ECO:0000259|PROSITE:PS50137"
FT   DOMAIN          289..356
FT                   /note="DRBM"
FT                   /evidence="ECO:0000259|PROSITE:PS50137"
FT   DOMAIN          421..749
FT                   /note="A to I editase"
FT                   /evidence="ECO:0000259|PROSITE:PS50141"
FT   REGION          59..110
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        59..77
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   753 AA;  84107 MW;  65D891ABE2E0B5A1 CRC64;
     AHLLSGYGRG LGPLDKKEGS FGFELLLKII TKKPQNIIYK VSMLSALIAP FKYISPGTSS
     TEDEDSLSTS SAEVKENRNI GNLEDRSIGP GECQSTRSGS SGLKRKRPLE EDNNGHLCQL
     RLIYKKLSWS EAPKNALVQL NELRPGLQYR MVSQTGPVHA PVFSIVVEVN GLTFEGTGPT
     KKKAKMRAAE LALKSFIQFP NAPQAHLAMG NISNPSADFT SDQADFPDTL FKEFESSSCS
     DRLSLCNSET ESELLSSELL RHGRLLRHTL DLMVQAQQRL GGIVQESEAP KSPVAVLNEL
     RPGLRYACLS ERAEGRRLRS FVMAVRVDGR IFEGYGRSKK LAKNQAAQYA LQALFNIRTA
     PEGRTGSDCV FQDFADSIFH LVREKYRSLV GGCSPVHARH KSLAGIVMTR GLDLRHAQVV
     ALSTGTKCIN GEYLSDQGQV VNDCHAEVTA RRALLRFLYS QLELFVSKRP EDWEESIFVH
     HKECGYRLRD NIHFHMYIST SPCGDGRLNS PYEITADLHS SRHLMRKHRS HLRTKIESGE
     GTVPVRCRGP AQTWDGVLQG EHLITMSCTD KLTRWNILGL QGALLSHFVE PVYLHSMTVG
     SLRHTGHLGR VLNQRQERLG PLPATYRRNQ PLLSGLSSAD YQQPGKASCV SVNWTLGDAQ
     LEVVNTATGR RRDSGTPSRL CKHALFTRWN RLYRKLGIHA SSSADRQLMY GEAKMAARPY
     QTAKQQWFRS LQEMGLGTWV KKPPEQEQFL LSD
//