ID A0A3B4HA68_9CICH Unreviewed; 222 AA.
AC A0A3B4HA68;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=Platelet-derived growth factor (PDGF) family profile domain-containing protein {ECO:0000259|PROSITE:PS50278};
OS Pundamilia nyererei.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Pundamilia.
OX NCBI_TaxID=303518 {ECO:0000313|Ensembl:ENSPNYP00000030453.1, ECO:0000313|Proteomes:UP000261460};
RN [1] {ECO:0000313|Ensembl:ENSPNYP00000030453.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the PDGF/VEGF growth factor family.
CC {ECO:0000256|RuleBase:RU003818}.
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DR AlphaFoldDB; A0A3B4HA68; -.
DR STRING; 303518.ENSPNYP00000030453; -.
DR Ensembl; ENSPNYT00000031194.1; ENSPNYP00000030453.1; ENSPNYG00000022957.1.
DR GeneTree; ENSGT00940000156167; -.
DR Proteomes; UP000261460; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR CDD; cd00135; PDGF; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR000072; PDGF/VEGF_dom.
DR PANTHER; PTHR12025; VASCULAR ENDOTHELIAL GROWTH FACTOR; 1.
DR PANTHER; PTHR12025:SF3; VASCULAR ENDOTHELIAL GROWTH FACTOR C; 1.
DR Pfam; PF00341; PDGF; 1.
DR SMART; SM00141; PDGF; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS50278; PDGF_2; 1.
PE 3: Inferred from homology;
KW Growth factor {ECO:0000256|RuleBase:RU003818};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..222
FT /note="Platelet-derived growth factor (PDGF) family profile
FT domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017461923"
FT DOMAIN 117..209
FT /note="Platelet-derived growth factor (PDGF) family
FT profile"
FT /evidence="ECO:0000259|PROSITE:PS50278"
SQ SEQUENCE 222 AA; 25491 MW; AF87554399B7AC9C CRC64;
MWIPAVLLWM LNISNLCSGQ DYTDYYQSGD MGTQSNDQLS LETIKSVDDL LQFLYPEYSV
IQQCLKKRSW HSSSSPSSSS LSTSSMSPLL NANNQDMWVP MREEALYKVD DTWRVILEEI
QRTSCQPREV CIEVAKEYPE STSQFYLPHC VALHRCSGCC NNEAFYCTNT SYTLVNKTLM
ERSQSRLDYT AVTVTFINHT SCDCLPKRPL RSIIRRAATD RL
//
