ID   A0A3B4HDD2_9CICH        Unreviewed;       670 AA.
AC   A0A3B4HDD2;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=Adenosine deaminase RNA specific B2 (inactive) {ECO:0000313|Ensembl:ENSPNYP00000032123.1};
GN   Name=ADARB2 {ECO:0000313|Ensembl:ENSPNYP00000032123.1};
OS   Pundamilia nyererei.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Pundamilia.
OX   NCBI_TaxID=303518 {ECO:0000313|Ensembl:ENSPNYP00000032123.1, ECO:0000313|Proteomes:UP000261460};
RN   [1] {ECO:0000313|Ensembl:ENSPNYP00000032123.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B4HDD2; -.
DR   Ensembl; ENSPNYT00000032893.1; ENSPNYP00000032123.1; ENSPNYG00000024249.1.
DR   GeneTree; ENSGT00940000157252; -.
DR   Proteomes; UP000261460; Unplaced.
DR   GO; GO:0004000; F:adenosine deaminase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   Gene3D; 3.30.160.20; -; 2.
DR   InterPro; IPR002466; A_deamin.
DR   InterPro; IPR014720; dsRBD_dom.
DR   PANTHER; PTHR10910:SF17; DOUBLE-STRANDED RNA-SPECIFIC EDITASE B2; 1.
DR   PANTHER; PTHR10910; EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN; 1.
DR   Pfam; PF02137; A_deamin; 1.
DR   Pfam; PF00035; dsrm; 2.
DR   SMART; SM00552; ADEAMc; 1.
DR   SMART; SM00358; DSRM; 2.
DR   SUPFAM; SSF54768; dsRNA-binding domain-like; 2.
DR   PROSITE; PS50141; A_DEAMIN_EDITASE; 1.
DR   PROSITE; PS50137; DS_RBD; 2.
PE   4: Predicted;
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00266}.
FT   DOMAIN          78..144
FT                   /note="DRBM"
FT                   /evidence="ECO:0000259|PROSITE:PS50137"
FT   DOMAIN          264..301
FT                   /note="DRBM"
FT                   /evidence="ECO:0000259|PROSITE:PS50137"
FT   DOMAIN          354..661
FT                   /note="A to I editase"
FT                   /evidence="ECO:0000259|PROSITE:PS50141"
SQ   SEQUENCE   670 AA;  73991 MW;  8049A3FBA60E5C0D CRC64;
     FQPPDLTGTS SLEVKENQDD KCQVERVLLR KYHPSTFCTT FPKNGQRALK RKQPLVDGKD
     QLLYQSHSTC KRAAWGVTQK NALVHLNELR PGLQYDITSK TGPLHAPVFS VAVEVNGFHF
     EGRGPTKKQA KMRAAEQALQ SFIQFPNASQ AHATMGNFTS TPVDFTADKV DIPNGFFKEF
     EPSVLRNCDL LHCNAAKKEV FSSIYNHRRL VRLTLDLVSS TNPKRRAVTT SLLEDLSPVA
     LLSELRPGLR YMCLTERVPG RPMKTFVMVV RLEGRVFEGC APSKRLAKAK AAATALQSLY
     NISLGPERTF MGLQDSRAKN QLPQSQSQSS CLSIPTCFIS LPPGLDLRSA QVVSLATGTK
     CLDLGGVSDC GCTLTDCHAE VVSRRALVRF LYSQLELKPV DSEDQSIFTP NKSCGDGFRL
     REGVHFHMYV SSSPCGDARL NCPYETTAAC ERNTFRLFNR RFRCHLRVKV KGGEGTLPIT
     ARRANQKWDG LSPSKPLVTM SCTDKLAKWS VVGLQGALLS HLVEPVYLQS LTVGTLSHTG
     HLGRAMARRL APIKHLPFPY RRQQLLLGLS SRDARPAGKP PNVSVNWSCG DGGWEEISTS
     TGRRKDSGTP SRLCRQSTTG TYCASKMSAQ CYQRAVQQFS SALQGGGLGT WLRKPPKLGH
     FTVSVSKTER
//