ID   A0A3B4T8X2_SERDU        Unreviewed;       889 AA.
AC   A0A3B4T8X2;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Transportin 2 {ECO:0000313|Ensembl:ENSSDUP00000002412.1};
OS   Seriola dumerili (Greater amberjack) (Caranx dumerili).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Carangaria; Carangiformes; Carangidae; Seriola.
OX   NCBI_TaxID=41447 {ECO:0000313|Ensembl:ENSSDUP00000002412.1, ECO:0000313|Proteomes:UP000261420};
RN   [1] {ECO:0000313|Ensembl:ENSSDUP00000002412.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC       Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   AlphaFoldDB; A0A3B4T8X2; -.
DR   Ensembl; ENSSDUT00000002476.1; ENSSDUP00000002412.1; ENSSDUG00000001767.1.
DR   GeneTree; ENSGT00940000156708; -.
DR   OMA; ACDFWVQ; -.
DR   OrthoDB; 276400at2759; -.
DR   Proteomes; UP000261420; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR000357; HEAT.
DR   InterPro; IPR001494; Importin-beta_N.
DR   InterPro; IPR040122; Importin_beta.
DR   PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR   PANTHER; PTHR10527:SF17; TRANSPORTIN-2; 1.
DR   Pfam; PF02985; HEAT; 1.
DR   Pfam; PF13513; HEAT_EZ; 1.
DR   Pfam; PF03810; IBN_N; 1.
DR   SMART; SM00913; IBN_N; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE   4: Predicted;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          31..99
FT                   /note="Importin N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50166"
FT   REGION          340..367
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        352..367
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   889 AA;  100356 MW;  E67C2EF42DABB641 CRC64;
     MEWQPDEQGL QQVLQLLKDS QSPNTVTQRA VQQKLEQLNQ FPDFNNYLIF VLTRLKTEDE
     PTRSLSGLIL KNNVKAHYQN FPPAVADFIK KECLNNIGDP SPLIRATIGI LITTIASKGE
     LQTWPELLPQ LCNLLNSEDY NTCEGSFGAL QKICEDSSEL LDSDALNRPL NIMIPKFLQF
     FKHCSPKIRS HAIACVNQFI IGRAQALMDN IDTFIESLFA LAADEDSEVR KNVCRALVML
     LEVRIDRLIP HMHSIIQYML QRTQDPDENV ALEACEFWLT LAEQPICKEM LSGHLVQLIP
     ILVNGMKYSE IDIILLKGDV EEDEAVPDSD QDIKPRFHKS RTVTLQHEGG EGEEGEDIEE
     DDDDDDDTLS DWNLRKCSAA ALDVLANVFR DELLPHLLPL LKGLLFHPDW VIKESGILVL
     GAIAEGCMQG MVPYLPELIP HLIQCLCDKK ALVRSIACWT LSRYAHWVVS QPPDSYLKPL
     MTELLKRILD GNKRVQEAAC SAFATLEEEA CTELVPYLSF ILDTLVFAFG KYQHKNLLIL
     YDAIGTLADS VGHHLNQPEY IQKLMPPLIA KWNELKDEDK DLFPLLECLS SVATALQSGF
     LPYCEPVYQR CVTLVQKTLA QAMMYNQHPD QYEAPDKDFM IVALDLLSGL AEGLGGNVEQ
     LVARSNIMTL LFQCMQDTMP EVRQSSFALL GDLTKACFLH VKPCIAEFMP ILGLNLNPEF
     ISVCNNATWA IGEISMQMGA EMQPYVGMVL PHLVEIINRP NTPKTLLENT AITIGRLGYV
     CPQEVAPQLQ HFIRPWCTSL RNIRDNEEKD SAFRGICVMI GVNPAGVVQD FIFFCDAVAS
     WVNPKDDLRD MFYKILHGFK DQVGEENWQQ FSEQFPPLLK ERLSACYGV
//