ID A0A3B4TAK4_SERDU Unreviewed; 1709 AA.
AC A0A3B4TAK4;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Trinucleotide repeat-containing gene 6C protein-like {ECO:0000313|Ensembl:ENSSDUP00000003131.1};
GN Name=TNRC6C {ECO:0000313|Ensembl:ENSSDUP00000003131.1};
OS Seriola dumerili (Greater amberjack) (Caranx dumerili).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=41447 {ECO:0000313|Ensembl:ENSSDUP00000003131.1, ECO:0000313|Proteomes:UP000261420};
RN [1] {ECO:0000313|Ensembl:ENSSDUP00000003131.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the GW182 family.
CC {ECO:0000256|ARBA:ARBA00007302}.
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DR STRING; 41447.ENSSDUP00000003131; -.
DR Ensembl; ENSSDUT00000003204.1; ENSSDUP00000003131.1; ENSSDUG00000002366.1.
DR GeneTree; ENSGT00940000157598; -.
DR OMA; VSWPPEF; -.
DR Proteomes; UP000261420; Unplaced.
DR GO; GO:0005829; C:cytosol; IEA:UniProt.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR CDD; cd14283; UBA_TNR6C; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR InterPro; IPR019486; Argonaute_hook_dom.
DR InterPro; IPR026805; GW182_M_dom.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR041917; TNR6C_UBA.
DR InterPro; IPR032226; TNRC6_PABC-bd.
DR InterPro; IPR015940; UBA.
DR InterPro; IPR009060; UBA-like_sf.
DR PANTHER; PTHR13020; TRINUCLEOTIDE REPEAT-CONTAINING GENE 6; 1.
DR PANTHER; PTHR13020:SF9; TRINUCLEOTIDE REPEAT-CONTAINING GENE 6C PROTEIN; 1.
DR Pfam; PF10427; Ago_hook; 1.
DR Pfam; PF12938; M_domain; 1.
DR Pfam; PF00076; RRM_1; 1.
DR Pfam; PF16608; TNRC6-PABC_bdg; 2.
DR Pfam; PF00627; UBA; 1.
DR SMART; SM00165; UBA; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR SUPFAM; SSF46934; UBA-like; 1.
DR PROSITE; PS50030; UBA; 1.
PE 3: Inferred from homology;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW Translation regulation {ECO:0000256|ARBA:ARBA00022845}.
FT DOMAIN 982..1027
FT /note="UBA"
FT /evidence="ECO:0000259|PROSITE:PS50030"
FT REGION 81..981
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1077..1114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1211..1380
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1400..1421
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1464..1495
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1625..1661
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 98..182
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 194..216
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 255..322
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 349..376
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 502..563
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 581..601
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 608..631
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 725..747
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 778..811
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 821..837
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 864..894
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 947..971
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1094..1108
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1211..1228
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1256..1280
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1295..1324
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1344..1380
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1402..1421
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1638..1657
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1709 AA; 178227 MW; 128458F947617C7A CRC64;
MTYMTYTSLH SSFCSCSYPI PSLSHAELPP QSGQGAQYDN PLWGHLPANR STTSAASSTN
LSGWDQLIID QKDTEAWPSI TLSQSQAPPG GCPLDTDPGR LTSSSSSTSS SCSTVSMATG
ANSQTGHFPA NHLSSKANSG PSPANHTGTN MLSSQVAANR SWGSGPGPSH CPPQSSVGNE
GKSDSPVGGA GGRGWGSSSS SSTTNFNLNL NPNANPSAWP MLGHDGGGTG GGSSGGANTI
SPPQPTPNLC NPPGPPSAQT STCTGANTNS NSSGIGSAWG SIMTSDMSEA HPSPSTNVSF
SSEPQNLKTD GPNHTNKQEP PSPIRSLPGW GSASVGLGSM GQPPPGVPQV NGEDSSSVWG
HSGDSKAPSS KEASGWDSGW SHGGAGAGNS GGWGDQSGGD WGKQHTEEAQ GGWDAPSSPP
QDPQAGPWGR AVSTAAASEG SSDSMEGHNQ RRDRSSRDNP APLLPAQDLD PRVLCNTGWG
QTPVRQHTSW DMDDTKRKND VGTETWGSGP TTPSDAQGPS KTNIGPTQRT DSGSKNDVPG
SQGASGWGGS VAATNQPSSG WGEPPNNIKP PGGPGGWGNH PTGGPTTSVP KNGSQTWGEE
KSSGWDDSHI KTTSQGWGEQ PKASHGWGNS GASKNAGDWG EPEESKKSPT NPAWEGEAGG
WKEKPRGWGM PASAPGISGP GGNGGWGEQV SQRPSGPPQG WGGKPQDGPS CSGGAGGIGS
WGGSGSVKQG GSWGGSKQES SAEPTGWEEP SPPSIRRKME IDDGTSAWGD PGSYNKAVNL
WDRNNPGMSQ AKVTTGGNNP PGPNNNHPHS HNHPYHGPPA PLQNHSQNSQ NPGPTSGPMD
PVVQHQPGPS HNRGPLIAQG WGDLPSSHTK SESSWGEPAP SPVSVDNGTS AWGKPSGSCG
GWGDGNPDSY GRGNPTMTTA SCKPAPKPMQ DGWGGGGEEL SQWDAEEGDM WNSTASQESN
SSCNSWGNAS KKGPQKGKVP GKQEDAWMMN RLIKQLTDMG FPRDPAEEAL KSNNMNLDQA
MSALLEKKTE LDKRGMGIAG HDYNNGLINK PMSCPRPPLL SKDPSADPRL PFMDKMQSGM
FGGGGAAQAR TMQQPQPPPQ PPVPPLSSSQ PSLRAQVPQF LSPQVQAQLL QFAAKNIGLN
PALLTSPINP QHMTLLNQLY QLQLAYQRLQ IQQQMLQAQR NVSGPIRQQE QQVARTINNM
QQQIQQHQRQ LAQALLMKQQ QQQPPPSHSG LHPGGAKSTL DSFPGHPHAP GLPDLQTKEP
QSSPNTYSHY SLSGLNPNMN VNCMEVGGLS MKEPPQPQSR LSQWTHPNSI ESLSGSSSPL
EPSLGKHGSN LGPPGKPPQL EDSYSPYNLM SSSESPTSPL VPPDSWGQGK SSSDKMANGT
NINWPPEFCP GVPWKGLQNI DPETDPNVTP GSVPSGPTIN TNIQDVNRYL LRDRSGGKLS
EMKSTWSPGP ISHSQASLSH ELWKVPQGPR SSTTAPSRPP PGLTNTKPSS TWGGNSLGLA
QGWSSSYTSA GTTWSTDSST RTSSWLVLRN LTPQIDGSTL RTLCMQHGPL ITFHLNLTQG
NAVVRYSSKD EAAKAQKSLH MCVLGNTTIL AEFAGEEEVN RFFAQGQSLG GTTSWQATPG
TNQTRMGGTG SGASHPIGHS PHWNNNNGSS SSSGLGAGGA KTGGELLWGG VQQYSSLWGP
PSGEEGRVMG SPTPINTLLP GDLLSGESM
//
