ID A0A3B4TAT2_SERDU Unreviewed; 370 AA.
AC A0A3B4TAT2;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=HERV-H LTR-associating 2b, tandem duplicate 2 {ECO:0000313|Ensembl:ENSSDUP00000003211.1};
OS Seriola dumerili (Greater amberjack) (Caranx dumerili).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=41447 {ECO:0000313|Ensembl:ENSSDUP00000003211.1, ECO:0000313|Proteomes:UP000261420};
RN [1] {ECO:0000313|Ensembl:ENSSDUP00000003211.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR AlphaFoldDB; A0A3B4TAT2; -.
DR Ensembl; ENSSDUT00000003286.1; ENSSDUP00000003211.1; ENSSDUG00000002467.1.
DR GeneTree; ENSGT00940000163670; -.
DR OMA; ITCISEM; -.
DR Proteomes; UP000261420; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0002682; P:regulation of immune system process; IEA:UniProt.
DR CDD; cd00096; Ig; 1.
DR CDD; cd16091; IgV_HHLA2; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR25466:SF14; CD276 ANTIGEN HOMOLOG-RELATED; 1.
DR PANTHER; PTHR25466; T-LYMPHOCYTE ACTIVATION ANTIGEN; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 2.
DR SMART; SM00406; IGv; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR PROSITE; PS50835; IG_LIKE; 3.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..370
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017366609"
FT TRANSMEM 318..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 6..109
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 136..212
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 227..305
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 370 AA; 41456 MW; 45123F09EDB119E6 CRC64;
MSETKPVVFL LLKLLWTLTR GDTEVSCVFM ESCILPCSFQ DDTDVVIHWN NVTAGNIPVH
SFYYNKDQFS HQDQRFRNRT SLFKDQISGG NASLQLTGLQ VQDQGRYKCY TGTNRGRNES
FINLKVDAPV GKVDLQQVGN RITCSSEGIF PEPELTWSTS PPSTVTLKSQ AEVQETEQLL
YNITSSLTVS DSDSDLSYSC SISTRRNKRR ATLFKTTFLN VSNTGTTIPC AASNSSFKSL
IWRFNHSLII LTQTRADVSS SVSEGWRQQV KGVSESGSLM LQNLSPHHGG IYTCELSDAE
ETLITNTFLR IQSPDKALII HGVIPGVLAA AVLVLAAVVL VWYCKLKKGE QRNRKRESQT
TIKHQREWMR
//
