ID A0A3B4TH37_SERDU Unreviewed; 1298 AA.
AC A0A3B4TH37;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Roundabout homolog 2-like {ECO:0000313|Ensembl:ENSSDUP00000005504.1};
GN Name=ROBO3 {ECO:0000313|Ensembl:ENSSDUP00000005504.1};
OS Seriola dumerili (Greater amberjack) (Caranx dumerili).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=41447 {ECO:0000313|Ensembl:ENSSDUP00000005504.1, ECO:0000313|Proteomes:UP000261420};
RN [1] {ECO:0000313|Ensembl:ENSSDUP00000005504.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR Ensembl; ENSSDUT00000005607.1; ENSSDUP00000005504.1; ENSSDUG00000003540.1.
DR GeneTree; ENSGT00940000155457; -.
DR OMA; LMMSHTH; -.
DR Proteomes; UP000261420; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 3.
DR CDD; cd07693; IgC_1_Robo; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 8.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR PANTHER; PTHR44170:SF37; ROUNDABOUT GUIDANCE RECEPTOR 3; 1.
DR Pfam; PF00041; fn3; 3.
DR Pfam; PF07679; I-set; 3.
DR Pfam; PF13927; Ig_3; 2.
DR SMART; SM00060; FN3; 3.
DR SMART; SM00409; IG; 5.
DR SMART; SM00408; IGc2; 5.
DR SMART; SM00406; IGv; 3.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50853; FN3; 3.
DR PROSITE; PS50835; IG_LIKE; 5.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 836..858
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 18..114
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 120..207
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 212..296
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 301..394
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 405..491
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 512..607
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 626..718
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 723..820
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 1035..1054
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1063..1132
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1266..1298
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1039..1053
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1066..1090
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1101..1126
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1274..1290
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1298 AA; 143425 MW; A98820BD5C92EEDA CRC64;
FFNLYLTRSR ARFEDGTPRI VEDPSDLIVS KGEPATLNCK AEGRPTPSIE WYKDGERVET
DKDDPRSHRM LLPSGSLFFL RIVHGRRSKP DEGVYTCVAR NYLGEAISRN ASLEVAILRD
DFRQAPSDVV VAAGEPAVLE CVPPRGHPEP TVSWKRNNVR VSTKDERISM RGGKLMISHT
RKSDAGMYVC VGTNMVGERD SDPAELVVYE RPVLVRRPVN QVVMEEETVD FLCEVHGDPA
PTVRWRREEG ELPRGRFEIR NGNSLRLFRV KEQDEGTYTC TSENSVGKTE ASAMLQVHVP
PQIASKPRDQ ITTQGRSVTF QCGTTGNPPP AIFWQKEGSQ MLLFPGQPPS QSGRYSVSMS
GELTITDVHP EDSGFYICQA ISVAGSVLTK ALLEVEGGPS GRVPPIIRQG PSNQTVSQGA
TAQLHCRVIG GPSVKISWEK DGERLQGNKP RLTLMDNGTL QITDIKDSDS GMYTCIVSSA
TGETSWSGML TVREDGVPPV SRVSEFIQLP GPPQKPVVTE VTKNTVTLTW QSNPHEGGAA
VTSYIIEAFS QSVGSTWQTV ADHVKQERHT VVELFPNTVY LFIVRAVNSY GLSDPSPISE
PVRTQDGSPT EQGVDHRQVQ RELGEVSVYL QKPVVLSPTS ARISWTVARQ SRYVQGYRIF
YRTIGNSWLV QDVEDTSDHS TILVDLHSST EYEVKIRPYF NELQGHDSLM VLLRTPEEVS
SAPPQAVSVV QLTNSSSISV SWEPPPHNIQ SGIIREYKVW CLGSDVDQEN QINRTVDGAV
LSILLTGLLP DVHYSVMVAA VTSLGVGAQS PPVSLLLSES LKLISEQITS VVRQPAFIAG
LGVAAWLVLM GFSGWLYCRH RRRKQLGHYT TSFAYTPAVG FAHSEGSGII NGGPGLLGSN
MGNYPWLADS WPTPNLTHNS KDSVNCCSGK LDSDRYYNTV GIINYPNQSE KRSTASNDSP
IYSTINTVAE DDLLAYYDTY SSTSYNQGPD PYSSNPGLSN SGLVGLEQDL DQWTIQSGQS
GSEYAKLQYT KKSNDKLVKQ KSTGSSSKSP PLTWVDVLSL PLPAKDKGHT KADKREEQHS
SEEEDDDWCP PLPARTYLMD TSREEVSSLP SKPDAATLLT SPQRDTHKPS DSPRLQHFDL
LARHHSSQVS QSNPDLFTNT KARDGSEVYH TNQWADNFKG ESLDKGQLEF SLMWHIFGNC
FPRGSAQPHS VMYNLVYDIT SQKVFVHENH VAFIQSAAQC SLVSSKCPED DISVLPCQDN
LLLQLASRTP QPRHTDPGVR RKRPRKDNSS ESYTAKQV
//
