ID A0A3B4TLF1_SERDU Unreviewed; 448 AA.
AC A0A3B4TLF1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=V-type proton ATPase subunit S1-like {ECO:0000313|Ensembl:ENSSDUP00000006817.1};
OS Seriola dumerili (Greater amberjack) (Caranx dumerili).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=41447 {ECO:0000313|Ensembl:ENSSDUP00000006817.1, ECO:0000313|Proteomes:UP000261420};
RN [1] {ECO:0000313|Ensembl:ENSSDUP00000006817.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the vacuolar ATPase subunit S1 family.
CC {ECO:0000256|ARBA:ARBA00009037}.
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DR AlphaFoldDB; A0A3B4TLF1; -.
DR STRING; 41447.ENSSDUP00000006817; -.
DR Ensembl; ENSSDUT00000006949.1; ENSSDUP00000006817.1; ENSSDUG00000005025.1.
DR GeneTree; ENSGT00940000156650; -.
DR OMA; MSQRFYP; -.
DR OrthoDB; 2878970at2759; -.
DR Proteomes; UP000261420; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0045176; P:apical protein localization; IEA:Ensembl.
DR GO; GO:0003140; P:determination of left/right asymmetry in lateral mesoderm; IEA:Ensembl.
DR GO; GO:0008057; P:eye pigment granule organization; IEA:Ensembl.
DR GO; GO:0070121; P:Kupffer's vesicle development; IEA:Ensembl.
DR GO; GO:0032438; P:melanosome organization; IEA:Ensembl.
DR GO; GO:0072659; P:protein localization to plasma membrane; IEA:Ensembl.
DR GO; GO:0042127; P:regulation of cell population proliferation; IEA:Ensembl.
DR GO; GO:0030641; P:regulation of cellular pH; IEA:Ensembl.
DR GO; GO:1902017; P:regulation of cilium assembly; IEA:Ensembl.
DR GO; GO:1901207; P:regulation of heart looping; IEA:Ensembl.
DR GO; GO:0003406; P:retinal pigment epithelium development; IEA:Ensembl.
DR Gene3D; 2.40.160.110; -; 1.
DR InterPro; IPR008388; Ac45_acc_su.
DR InterPro; IPR046756; VAS1/VOA1_TM.
DR InterPro; IPR046755; VAS1_LD.
DR PANTHER; PTHR12471:SF2; V-TYPE PROTON ATPASE SUBUNIT S1; 1.
DR PANTHER; PTHR12471; VACUOLAR ATP SYNTHASE SUBUNIT S1; 1.
DR Pfam; PF20520; Ac45-VOA1_TM; 1.
DR Pfam; PF05827; VAS1_LD; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 404..423
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 247..382
FT /note="V-type proton ATPase subunit S1 luminal"
FT /evidence="ECO:0000259|Pfam:PF05827"
FT DOMAIN 398..436
FT /note="V-type proton ATPase subunit S1/VOA1 transmembrane"
FT /evidence="ECO:0000259|Pfam:PF20520"
SQ SEQUENCE 448 AA; 48458 MW; 4A7AD7EC51DBD6D9 CRC64;
MAGPRCSGKV RLTAFIAIFF AFFATGSSTA QVPLLMWSSD GLPPLALPAA GHIISNDQLT
AYLTTALGSG PHTVLLFLQD KLSKDDFTVF GGVFGNKQDS AFQNLEAAVQ TSSSSVTLPA
LEWSGSSAIL ALLQEKLGVS PLLVDADTLS HLSINTSVSN LLLINLPYCT GLHKSCKEVL
HNNDEIIGEV LGIMKTKNVP YTAIYTGLQP SRVISETSVS DQSVGRSLLQ AIAPDVRPIM
FNVSGSPCIM LWAQNLNISL SSSSAWIDLA AETPSLEGSM CNSSNSVLVL NYSSGYTLSF
AMSQRFYPVS ARNWFTLDSV QLQSNGLTAS FIGRRGIYAP AEYSFHCQSV NSFQDALLVP
NNTNQNTTQW RLKFIDFQIQ GFGLANGTNF SYANDCAGFF TPGIWMGLLT SLLMLLIFVY
GLHMIMQLNT MDRFDDPKGP SISVPQSE
//
