ID A0A3B4TNR1_SERDU Unreviewed; 380 AA.
AC A0A3B4TNR1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=Thromboxane A2 receptor {ECO:0000256|ARBA:ARBA00017628};
DE AltName: Full=Prostanoid TP receptor {ECO:0000256|ARBA:ARBA00029815};
GN Name=PTGIR {ECO:0000313|Ensembl:ENSSDUP00000007667.1};
OS Seriola dumerili (Greater amberjack) (Caranx dumerili).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=41447 {ECO:0000313|Ensembl:ENSSDUP00000007667.1, ECO:0000313|Proteomes:UP000261420};
RN [1] {ECO:0000313|Ensembl:ENSSDUP00000007667.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000256|RuleBase:RU000688}.
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DR AlphaFoldDB; A0A3B4TNR1; -.
DR STRING; 41447.ENSSDUP00000007667; -.
DR Ensembl; ENSSDUT00000007806.1; ENSSDUP00000007667.1; ENSSDUG00000005631.1.
DR GeneTree; ENSGT01050000244902; -.
DR OMA; FAVFVCN; -.
DR OrthoDB; 5355693at2759; -.
DR Proteomes; UP000261420; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016501; F:prostacyclin receptor activity; IEA:Ensembl.
DR GO; GO:0004960; F:thromboxane receptor activity; IEA:InterPro.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR008365; Prostanoid_rcpt.
DR InterPro; IPR001105; Thbox_rcpt.
DR PANTHER; PTHR11866; G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER; 1.
DR PANTHER; PTHR11866:SF7; PROSTACYCLIN RECEPTOR; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR01788; PROSTANOIDR.
DR PRINTS; PR00429; THROMBOXANER.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW G-protein coupled receptor {ECO:0000256|RuleBase:RU000688};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|RuleBase:RU000688};
KW Transducer {ECO:0000256|RuleBase:RU000688};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000688};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 35..54
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 66..89
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 109..130
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 150..170
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 207..230
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 267..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 44..320
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
SQ SEQUENCE 380 AA; 42035 MW; 7E0DBAA65E01A8CF CRC64;
MLDMNKSMVS NESCHNTTCN DVLAVNEDGK PATSIIMFLA GVVGNLLALF ILGVHQKEHR
SRSSVFCILV TGLALTDLLG TCLLSPPVFI CYARNMSLIS LGGKNLCNLF GFAMSFFGLA
PTLILCAMAV ERCLAISHPY FYSVHIRRSF AKFALFFIYF FSLAFCLLPY SGYGKFRQYC
PGTWCFIDMD ATGDDQVNLV LAFSLSYSSL MALLIFAVFV CNGSVIVSLC QMHRSQVMRR
GSVGSTGRRR RLSLAWFGQG EEEMDHLVLL ALITVIFVVC SLPLTIAGFI NAIHPFCGDT
ENLTAFRFYA LNPIVDPWVF IICRKSVFRH LCSLLSCSFS KGAVKTTAHC ALSLPLDSHI
QCNPPDRPVS QTNMYSNLPL
//
