ID A0A3B4TUE1_SERDU Unreviewed; 593 AA.
AC A0A3B4TUE1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=CBFA2/RUNX1 partner transcriptional co-repressor 3 {ECO:0000313|Ensembl:ENSSDUP00000009623.1};
GN Name=CBFA2T3 {ECO:0000313|Ensembl:ENSSDUP00000009623.1};
OS Seriola dumerili (Greater amberjack) (Caranx dumerili).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=41447 {ECO:0000313|Ensembl:ENSSDUP00000009623.1, ECO:0000313|Proteomes:UP000261420};
RN [1] {ECO:0000313|Ensembl:ENSSDUP00000009623.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B4TUE1; -.
DR Ensembl; ENSSDUT00000009810.1; ENSSDUP00000009623.1; ENSSDUG00000007029.1.
DR GeneTree; ENSGT00950000183176; -.
DR OMA; RASDPFY; -.
DR Proteomes; UP000261420; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003714; F:transcription corepressor activity; IEA:InterPro.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR Gene3D; 6.10.140.2220; -; 1.
DR Gene3D; 6.10.250.230; -; 1.
DR Gene3D; 1.20.120.1110; TAFH/NHR1 domain; 1.
DR InterPro; IPR013289; CBFA2T1/2/3.
DR InterPro; IPR014896; NHR2.
DR InterPro; IPR037249; TAFH/NHR1_dom_sf.
DR InterPro; IPR003894; TAFH_NHR1.
DR InterPro; IPR002893; Znf_MYND.
DR PANTHER; PTHR10379; MTG8 ETO EIGHT TWENTY ONE PROTEIN; 1.
DR PANTHER; PTHR10379:SF6; PROTEIN CBFA2T3; 1.
DR Pfam; PF08788; NHR2; 1.
DR Pfam; PF07531; TAFH; 1.
DR Pfam; PF01753; zf-MYND; 1.
DR PRINTS; PR01875; ETOFAMILY.
DR SMART; SM00549; TAFH; 1.
DR SUPFAM; SSF144232; HIT/MYND zinc finger-like; 1.
DR SUPFAM; SSF158553; TAFH domain-like; 1.
DR PROSITE; PS51119; TAFH; 1.
DR PROSITE; PS01360; ZF_MYND_1; 1.
DR PROSITE; PS50865; ZF_MYND_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00134}.
FT DOMAIN 85..180
FT /note="TAFH"
FT /evidence="ECO:0000259|PROSITE:PS51119"
FT DOMAIN 466..502
FT /note="MYND-type"
FT /evidence="ECO:0000259|PROSITE:PS50865"
FT REGION 1..78
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 201..258
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 512..593
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 405..447
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 28..78
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 201..227
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 514..593
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 593 AA; 65138 MW; 07C6A5235EBF2C92 CRC64;
MPDSPADVKT QPRSTPPTMP PPPPAVSQAT NRSASFTPTT MLNGSSHSPT SLNGAPSTPN
GFSNGPAMSS TASLSNQQLP PACGARQLCK LKRFLTTLQQ FGNDISPEIG ERVRSLVLGL
VNSTLTIEEF HSKLHEATNF PLRPFVIPFL KANLPLLQRE LLHCARLAKQ TPAQYLAQHE
QLLLDANASS PLDSSEIMLE MNEHGKRRTP DRTKDSSERE GLHPEHLAKR PCTISPSQRF
SPSTGLPAHP PPNVGPQHYR LEDMAMAHQY RDAYRHNEHR DARDRHRQTV HGARQEEVID
HRLTDREWAE EWKHLDNLLN CIMDMVEKTR RSLTVLRRCQ EADREEMNHW IRRYSDVEEM
KKGGSNGQHL CVCVCVSEIH RDFLHRPPSG YLPEEIWRKA EEAVNEVKRQ AMSELQKAVS
DAERKAHEMI SAERSKMERA LAEAKRQASE DALTVINQQE DSSESCWNCG RKASETCSGC
NTARYCGSFC QHKDWEKHHH VCGQGLQGLP GGSSVPLGTP SSSSSSSASS SAPPTHSEST
PPGPLSLAVQ SSIAGGAGNG SGSVSASPKE SSSSSASRST TPATPALLDG TSR
//
