ID A0A3B4TUP1_SERDU Unreviewed; 449 AA.
AC A0A3B4TUP1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Steroid hormone receptor ERR2-like {ECO:0000313|Ensembl:ENSSDUP00000010029.1};
OS Seriola dumerili (Greater amberjack) (Caranx dumerili).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=41447 {ECO:0000313|Ensembl:ENSSDUP00000010029.1, ECO:0000313|Proteomes:UP000261420};
RN [1] {ECO:0000313|Ensembl:ENSSDUP00000010029.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004334}.
CC -!- SIMILARITY: Belongs to the nuclear hormone receptor family.
CC {ECO:0000256|RuleBase:RU004334}.
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DR AlphaFoldDB; A0A3B4TUP1; -.
DR STRING; 41447.ENSSDUP00000010029; -.
DR Ensembl; ENSSDUT00000010221.1; ENSSDUP00000010029.1; ENSSDUG00000007271.1.
DR GeneTree; ENSGT00940000167036; -.
DR OMA; RYRAMKM; -.
DR Proteomes; UP000261420; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0042562; F:hormone binding; IEA:UniProt.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0033993; P:response to lipid; IEA:UniProt.
DR GO; GO:0014070; P:response to organic cyclic compound; IEA:UniProt.
DR CDD; cd07170; NR_DBD_ERR; 1.
DR Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 1.
DR Gene3D; 1.10.565.10; Retinoid X Receptor; 1.
DR InterPro; IPR035500; NHR-like_dom_sf.
DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR InterPro; IPR001723; Nuclear_hrmn_rcpt.
DR InterPro; IPR001628; Znf_hrmn_rcpt.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR PANTHER; PTHR48092:SF21; ESTROGEN-RELATED RECEPTOR GAMMA; 1.
DR PANTHER; PTHR48092; KNIRPS-RELATED PROTEIN-RELATED; 1.
DR Pfam; PF00104; Hormone_recep; 1.
DR Pfam; PF00105; zf-C4; 1.
DR PRINTS; PR00398; STRDHORMONER.
DR PRINTS; PR00047; STROIDFINGER.
DR SMART; SM00430; HOLI; 1.
DR SMART; SM00399; ZnF_C4; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR SUPFAM; SSF48508; Nuclear receptor ligand-binding domain; 1.
DR PROSITE; PS51843; NR_LBD; 1.
DR PROSITE; PS00031; NUCLEAR_REC_DBD_1; 1.
DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004334};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU004334};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU004334};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU004334};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU004334};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU004334};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU004334};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|RuleBase:RU004334}.
FT DOMAIN 109..184
FT /note="Nuclear receptor"
FT /evidence="ECO:0000259|PROSITE:PS51030"
FT DOMAIN 225..448
FT /note="NR LBD"
FT /evidence="ECO:0000259|PROSITE:PS51843"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 48..71
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 449 AA; 49095 MW; E8E8C158A1FCF5F4 CRC64;
TDEARSPASF LHSSPLSPSF PLDTTLTLSP THPAFLLPSP ASSSSSSSYS LLCGAPEPDS
PTGSSSSGGS VGGGAVVSEA SLRFTVSHTD SFSAQVKNIS EFFVLLIFSR LCLVCGDFAS
GFHYGVASCE ACKAFFKRTI QGNIEYSCPV MNECEITKRR RKACQACRFQ KCLQAGMMRE
GVRMDRVRGG RQKYKRRVET GLNLYTKGPY SHPVSNLYLI IVCLSGNKVI SHLLLTEPTP
LAANQDDSTN DSSLRTLLTL CDLLNRELLV LIGWAKQIPG FSGLSLVDQM SLLQSGWMEA
LLVGVAWRSQ GVAGEGLVFA GNLRLDEGQC RAAGLADLYE ALHHLTAKYQ VMNLSPEEVV
TLKAMALANS DADPVDCLES VQRFQDGLHE ALQEYESSRR EQHRTGRLLM SLPLLRQTAD
RAVKALLRLH HHRHVPLHKL LLEMLDAKA
//
