ID A0A3B4TWV4_SERDU Unreviewed; 393 AA.
AC A0A3B4TWV4;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Potassium calcium-activated channel subfamily N member 1 {ECO:0000313|Ensembl:ENSSDUP00000010527.1};
GN Name=KCNN1 {ECO:0000313|Ensembl:ENSSDUP00000010527.1};
OS Seriola dumerili (Greater amberjack) (Caranx dumerili).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=41447 {ECO:0000313|Ensembl:ENSSDUP00000010527.1, ECO:0000313|Proteomes:UP000261420};
RN [1] {ECO:0000313|Ensembl:ENSSDUP00000010527.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR AlphaFoldDB; A0A3B4TWV4; -.
DR Ensembl; ENSSDUT00000010724.1; ENSSDUP00000010527.1; ENSSDUG00000007649.1.
DR GeneTree; ENSGT00950000182904; -.
DR Proteomes; UP000261420; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR GO; GO:0016286; F:small conductance calcium-activated potassium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 2.
DR InterPro; IPR004178; CaM-bd_dom.
DR InterPro; IPR036122; CaM-bd_dom_sf.
DR InterPro; IPR015449; K_chnl_Ca-activ_SK.
DR InterPro; IPR013099; K_chnl_dom.
DR PANTHER; PTHR10153; SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL; 1.
DR PANTHER; PTHR10153:SF38; SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL PROTEIN 1; 1.
DR Pfam; PF02888; CaMBD; 1.
DR Pfam; PF07885; Ion_trans_2; 1.
DR Pfam; PF03530; SK_channel; 1.
DR SMART; SM01053; CaMBD; 1.
DR SUPFAM; SSF81327; Small-conductance potassium channel; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Calmodulin-binding {ECO:0000256|ARBA:ARBA00022860};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 36..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 78..96
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 127..151
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 163..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 196..216
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 234..304
FT /note="Calmodulin-binding"
FT /evidence="ECO:0000259|SMART:SM01053"
FT COILED 309..336
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 393 AA; 44298 MW; 1AE8C46101053DB6 CRC64;
KSLIALNLSF SSLLLQLFMV DNGADDWRIA MTLERILFVV FELLVCAIHP IPGQYVFTWT
ARLAFSYTAS VEDADVDIIL SVPMFLRLYL IGRVMLLHSK LFTDASSRSI GALNKINFDT
RFVMKTLMTI CPGTVLLVFS VSCWIIAAWT VRVCERYHDA QEVTSTFLGA MWLISITFLS
IGYGDMVPHT YCGKGVCLLT GIMGAGCTAL VVAVVARKSE LTRAEKHVHN FMMDTQLYKK
IKNTAANVLR ETWLIYKNTK LVKKIDHARV RHHQRKFLQA IHQLRRVKME CVICPPSCFQ
TQNMMYDLVS ELQHRSEELD RRIVALEEKL DSLLLSVQSL PVVLSHAITK LQKDFLDDLA
CRVHFLSSSL SSECCPVPAS SSLIIGTMHG LCG
//
