ID A0A3B4TX88_SERDU Unreviewed; 758 AA.
AC A0A3B4TX88;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Collagen type VIII alpha 1 chain {ECO:0000313|Ensembl:ENSSDUP00000010672.1};
GN Name=COL8A1 {ECO:0000313|Ensembl:ENSSDUP00000010672.1};
OS Seriola dumerili (Greater amberjack) (Caranx dumerili).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=41447 {ECO:0000313|Ensembl:ENSSDUP00000010672.1, ECO:0000313|Proteomes:UP000261420};
RN [1] {ECO:0000313|Ensembl:ENSSDUP00000010672.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498}.
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DR AlphaFoldDB; A0A3B4TX88; -.
DR STRING; 41447.ENSSDUP00000010672; -.
DR Ensembl; ENSSDUT00000010870.1; ENSSDUP00000010672.1; ENSSDUG00000007807.1.
DR GeneTree; ENSGT00940000158272; -.
DR OMA; KELPQMP; -.
DR Proteomes; UP000261420; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.40; -; 1.
DR InterPro; IPR001073; C1q_dom.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR008983; Tumour_necrosis_fac-like_dom.
DR PANTHER; PTHR15427:SF49; C1Q DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR15427; EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER; 1.
DR Pfam; PF00386; C1q; 1.
DR Pfam; PF01391; Collagen; 1.
DR PRINTS; PR00007; COMPLEMNTC1Q.
DR SMART; SM00110; C1Q; 1.
DR SUPFAM; SSF49842; TNF-like; 1.
DR PROSITE; PS50871; C1Q; 1.
PE 4: Predicted;
KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 625..758
FT /note="C1q"
FT /evidence="ECO:0000259|PROSITE:PS50871"
FT REGION 92..598
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 131..174
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 207..221
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 268..282
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 346..367
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 403..420
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 552..584
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 758 AA; 74066 MW; EBB38B08C1C5132C CRC64;
MSHNCLLRVA PSSCQALAMP PLPAPLFLTL LQFVVLTCVS GGAYYAHKQH PQQYQPVQQF
QHMGMGKDGF TQQQYLGKEV PYMQYPHYRK ELPQMPMHKG KENARKGAGY NGGQDKGQTI
PSGAEGIPQG EPGPAGPPGP EGPPGPPGPP GNGQPGPMGR PGPPGPPGVP AVGKPGLPGL
PGNAGGNGEA GPQGEMGPRG EEGPSGQPGP QGPPGPPGLP GIGKPGVQGL PGQPGPKGEP
GHKGLPGLPG LPGPKGDKGM GQPGQPGHKG LPGPPGPAGP RGLPGFGKPG LNGAPGPHGP
PGEKGHPGEQ GPAGVPGEGG QPGPPGLPGQ GKPGQNGLPG QPGMPGAKGH PGPPGLPGKP
GLPGFGKPGL PGPKGDKGMG GPPGHPGPKG DKGHGGLPGM LGPPGPNGTP GPPGPMGAPG
GLGAPGPKGD CGEGGPKGLD GAKGDTGPPG IPGKDGLPGD RGEPGPRGPP GPSGAKGDGG
HKGLPGTPGP PGLPGPKGQG GLPGNVGPQG PKGIPGMDGT AGPFGPPGLP GPKGDSGPPG
LPGIAGEGNP GLPGPMGPPG KEGLSGPPGQ PGQPGPPGPP GSPGLSPDMA GVLSEMGPGL
DGVKAGSYGK KGKYGGNGAE VMGANGLEMP AFTAVATTPF PPVGTPVVFD KLLYNGRQNY
NPQTGIFTCD MPGIYYFAYH IHCKGANVWV GLMRNNEPVM YTYDEYKKGF LDQASGSAVL
PLQPGDTVYL QLPSDQASGL YAGQYVHSSF SGYLLYPM
//
