ID   A0A3B4U2D5_SERDU        Unreviewed;       196 AA.
AC   A0A3B4U2D5;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   SubName: Full=TLE family member 5, transcriptional modulator {ECO:0000313|Ensembl:ENSSDUP00000012741.1};
OS   Seriola dumerili (Greater amberjack) (Caranx dumerili).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Carangaria; Carangiformes; Carangidae; Seriola.
OX   NCBI_TaxID=41447 {ECO:0000313|Ensembl:ENSSDUP00000012741.1, ECO:0000313|Proteomes:UP000261420};
RN   [1] {ECO:0000313|Ensembl:ENSSDUP00000012741.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the WD repeat Groucho/TLE family.
CC       {ECO:0000256|ARBA:ARBA00005969}.
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DR   AlphaFoldDB; A0A3B4U2D5; -.
DR   Ensembl; ENSSDUT00000012971.1; ENSSDUP00000012741.1; ENSSDUG00000009261.1.
DR   GeneTree; ENSGT01030000234519; -.
DR   Proteomes; UP000261420; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   InterPro; IPR005617; Groucho/TLE_N.
DR   InterPro; IPR009146; Groucho_enhance.
DR   PANTHER; PTHR10814; TRANSDUCIN-LIKE ENHANCER PROTEIN; 1.
DR   PANTHER; PTHR10814:SF4; TRANSDUCIN-LIKE ENHANCER PROTEIN 2; 1.
DR   Pfam; PF03920; TLE_N; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT   DOMAIN          15..128
FT                   /note="Groucho/TLE N-terminal Q-rich"
FT                   /evidence="ECO:0000259|Pfam:PF03920"
FT   REGION          172..196
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          23..50
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        175..196
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   196 AA;  22228 MW;  AAED081D5B28F17B CRC64;
     FFFPHLTHYA SSQQLKFTTS DSCDRIKDEF QFLQAQYHSL KLECDKLASE KSEMQRHYIM
     YYEMSYGLNI EMHKQAEIVK RLNGICAQVL PYLSQEHQQQ VLAAIERAKQ VTPPEMNSII
     RQQLQAHQLS QLQGLALPMT PLPLGLSQPT LPAVTTSSSL FSLSSLLASQ AQLAKEEKAS
     RDGVDSHREE DGDKSD
//