ID A0A3B4U5B0_SERDU Unreviewed; 539 AA.
AC A0A3B4U5B0;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Neuropilin and tolloid-like protein 1 {ECO:0000313|Ensembl:ENSSDUP00000013784.1};
GN Name=NETO1 {ECO:0000313|Ensembl:ENSSDUP00000013784.1};
OS Seriola dumerili (Greater amberjack) (Caranx dumerili).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=41447 {ECO:0000313|Ensembl:ENSSDUP00000013784.1, ECO:0000313|Proteomes:UP000261420};
RN [1] {ECO:0000313|Ensembl:ENSSDUP00000013784.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00059}.
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DR AlphaFoldDB; A0A3B4U5B0; -.
DR Ensembl; ENSSDUT00000014041.1; ENSSDUP00000013784.1; ENSSDUG00000010007.1.
DR GeneTree; ENSGT00940000156700; -.
DR OMA; PCERETF; -.
DR Proteomes; UP000261420; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00041; CUB; 2.
DR CDD; cd00112; LDLa; 1.
DR Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 1.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 2.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR023415; LDLR_class-A_CS.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR PANTHER; PTHR24251:SF27; NEUROPILIN AND TOLLOID-LIKE PROTEIN 1; 1.
DR PANTHER; PTHR24251; OVOCHYMASE-RELATED; 1.
DR Pfam; PF00431; CUB; 2.
DR Pfam; PF00057; Ldl_recept_a; 1.
DR SMART; SM00042; CUB; 2.
DR SMART; SM00192; LDLa; 1.
DR SUPFAM; SSF57424; LDL receptor-like module; 1.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 2.
DR PROSITE; PS01180; CUB; 2.
DR PROSITE; PS01209; LDLRA_1; 1.
DR PROSITE; PS50068; LDLRA_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00124}; Membrane {ECO:0000256|SAM:Phobius};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..539
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017394699"
FT TRANSMEM 347..369
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 45..159
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 176..291
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT REGION 434..473
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 485..513
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 435..471
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 488..513
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 45..72
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00059"
FT DISULFID 296..308
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 303..321
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 315..330
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
SQ SEQUENCE 539 AA; 61274 MW; A950E61535D73478 CRC64;
MIFLFSSSLL FSSSLLFFSS LLLSALAASL ISPQLSGATT TKKKCGAWVK EPQGGYFTSP
NYPEKYPPER ECVYIIEASP RQCIDLFFDD KYSIEPSWEC KFDHIEVRDG PFGFSPIIGR
YCGQESPAYV RSSGRYLYIK FVADGELEAI GFSARYNFTQ DPEFQELGAL PALPYCEFEL
SGPEGFVESA QIAREGQALQ TEAVDCRWYI RAPLRAKIYM RFMEYEMHNS NECKRNFVAI
YDGSSSVEHL KNKFCSTVAN DVMLVSSVGV VRLWADEGSR KSRFKILFTT FHEPPCEDDT
FFCHSNMCIN QTLVCNGIQN CVYPWDENHC KEKRKASILD TLDHTNLTII GVTCGLVVIL
LVISVIIQIK QPRKKYIIRR DDFDPALLHP GFEPPHYELC TLRRTPSGDL TDAAMAEDFE
KFHKLRRSSS KCIRDHHCGS QQGSVHGSVH GSRSNLSTRE TNTSPHLSYH TTPAGRRSIL
VMKHSYSQDG AERYRPEEED DLMMDDGPTT SQRHMHHHQI HHGMSGLDHT VHRTLSNDF
//
