ID   A0A3B4U6N8_SERDU        Unreviewed;      1267 AA.
AC   A0A3B4U6N8;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Erbb2 interacting protein {ECO:0000313|Ensembl:ENSSDUP00000014254.1};
OS   Seriola dumerili (Greater amberjack) (Caranx dumerili).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Carangaria; Carangiformes; Carangidae; Seriola.
OX   NCBI_TaxID=41447 {ECO:0000313|Ensembl:ENSSDUP00000014254.1, ECO:0000313|Proteomes:UP000261420};
RN   [1] {ECO:0000313|Ensembl:ENSSDUP00000014254.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A3B4U6N8; -.
DR   Ensembl; ENSSDUT00000014524.1; ENSSDUP00000014254.1; ENSSDUG00000010319.1.
DR   GeneTree; ENSGT00940000159526; -.
DR   Proteomes; UP000261420; Unplaced.
DR   CDD; cd00992; PDZ_signaling; 1.
DR   Gene3D; 2.30.42.10; -; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR036034; PDZ_sf.
DR   PANTHER; PTHR23119; DISCS LARGE; 1.
DR   PANTHER; PTHR23119:SF46; ERBB2-INTERACTING PROTEIN; 1.
DR   Pfam; PF13855; LRR_8; 3.
DR   Pfam; PF00595; PDZ; 1.
DR   SMART; SM00364; LRR_BAC; 6.
DR   SMART; SM00369; LRR_TYP; 9.
DR   SMART; SM00228; PDZ; 1.
DR   SUPFAM; SSF52058; L domain-like; 2.
DR   SUPFAM; SSF50156; PDZ domain-like; 1.
DR   PROSITE; PS51450; LRR; 4.
DR   PROSITE; PS50106; PDZ; 1.
PE   4: Predicted;
KW   Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          1176..1265
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   REGION          464..491
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          503..525
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          597..684
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          819..845
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          876..941
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          957..1055
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1124..1159
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        464..479
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        597..612
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        614..651
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        658..672
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        889..941
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        971..985
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        986..1000
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1026..1050
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1267 AA;  141146 MW;  A6CBF23BF9BD0684 CRC64;
     MTNNYIRQKY ENKTKRSLFV RLVPCRCLRG EEETVTSLDY SHCSLETVPK EIFSFEKTLQ
     ELYLDANQIE ELPKQLFNCQ LLHRLSMPDN DLTVLPAAIA NLINLRELDV SKNSIQEFPE
     NIKNCKVLAI VEASVNPISK LPEGFTQLLS LTQLYLNDAF LEFLPASFGR SVCSLVWIKM
     RLFLTQKKEA EVQTVHSGFT PEVLEQLTGI KELWMDGNRL TFLPGMLGML KQLVYLDVSK
     NNLEMVDEQI CGCESLQDLL LSNNALTQLP GSIGSLKKLT ALKVDENQLM YLPDSVGGLT
     SLEELDCSFN EIEALPSSVG QCVCMRTFAA DHNFLTQLPP EMGNWKNATV LFLHSNKLES
     LPEEMGDMQK LKVINLSNNK LKNLPYSFTK LNQMTAMWLS ENQSKPLIPL QKEEDPETHK
     TVLTNYMFPQ QTRTEDYIPN SDSESFNPTL WEEQRKHRAQ VAFECDEDKD ERETPPREGN
     LKRYPTPYPD ELKNMVKTAQ SVAHRLKEDE SSDESGKDPK PIERNHIGVQ DVGVKEFSQY
     KVKQERNEAL SEKCSFKKTI VFLQDSEELS DEEEEMKIAE MRPPLIEISI NQPKVVTLSK
     DKKDDGKDAD SLLDDTVANS NQNNSNCSSP SRMSDSVSLT TDSSQDNSLC TPEREAKMPF
     LPKSRQEDEN MNQPKDTTPL LHNGNGSETS LQALLKTQQT PPEKLGDYDL SMEARLAFIE
     KGINNGMENA YTKWDQINMN VSKLPTDNMV QLDELGKTKN GSVARDDLDS KQGFSNDNLE
     HLQNGNQQVS DCINSLGNKS QAMRVETSAV HVASTGVTAS SDMSLSRSTE ELSPDKRCHP
     PQVMKSHSVS NIETGGMRLY SFEGDDDSYD TAAMTRMAGA GPGPGAQGQS IVRSKSASQL
     LNEQTLQVYP SSSASSSDLL SSSKPPASTS RYPASSSMAM GIPPPQYNIQ YTSSAMPKDG
     LWSQRTPMPP EHQGYLPPPP PPHSLANTNY SNRNQAPPYP LQPQQRGPSM APKPSGDMWA
     KERLHSSGSQ PRSSTLQRQS STTSTASMGD PRRMQVPEGE YMTYRDIHTL ARGPLAMSQA
     MQRPLSARTY SIDVPGASRP LGARPQPHEL PERTMSVCDF NYQHGSPSKR PNTRVKSEHS
     LLDGPGQVSG GVGGGRVPAD WRDQVMRHIE AKKMEKMRVK VEKNPELGFS ISGGVGGRGN
     PFRPDDNGIF VTRVQPEGPA SKILQPGDKI IQANGYSFVN IDHGNAVSLL KTFPNTVDLI
     IVREMQA
//