ID A0A3B4UB44_SERDU Unreviewed; 2061 AA.
AC A0A3B4UB44;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Helicase with zinc finger {ECO:0000313|Ensembl:ENSSDUP00000015597.1};
OS Seriola dumerili (Greater amberjack) (Caranx dumerili).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=41447 {ECO:0000313|Ensembl:ENSSDUP00000015597.1, ECO:0000313|Proteomes:UP000261420};
RN [1] {ECO:0000313|Ensembl:ENSSDUP00000015597.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR STRING; 41447.ENSSDUP00000015597; -.
DR Ensembl; ENSSDUT00000015884.1; ENSSDUP00000015597.1; ENSSDUG00000011381.1.
DR GeneTree; ENSGT00940000156686; -.
DR OMA; KREMAPE; -.
DR OrthoDB; 5405202at2759; -.
DR Proteomes; UP000261420; Unplaced.
DR GO; GO:0004386; F:helicase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd18077; DEXXQc_HELZ; 1.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 4.10.1000.10; Zinc finger, CCCH-type; 1.
DR InterPro; IPR045055; DNA2/NAM7-like.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR049569; HELZ_DEAD-box_1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047187; SF1_C_Upf1.
DR InterPro; IPR000571; Znf_CCCH.
DR InterPro; IPR036855; Znf_CCCH_sf.
DR PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR PANTHER; PTHR10887:SF365; HELICASE WITH ZINC FINGER DOMAIN-RELATED; 1.
DR Pfam; PF13086; AAA_11; 2.
DR Pfam; PF13087; AAA_12; 1.
DR Pfam; PF00642; zf-CCCH; 1.
DR SMART; SM00356; ZnF_C3H1; 1.
DR SUPFAM; SSF90229; CCCH zinc finger; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50103; ZF_C3H1; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00723};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00723};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00723}.
FT DOMAIN 182..210
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT ZN_FING 182..210
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT REGION 1124..1195
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1282..1356
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1376..1504
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1586..1709
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1722..1741
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1762..1916
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1955..2040
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1143..1167
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1325..1345
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1383..1405
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1417..1443
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1626..1655
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1670..1699
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1722..1739
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1764..1823
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1847..1873
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1955..1981
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1982..1999
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2061 AA; 230343 MW; E88E8A7F846ACDE5 CRC64;
MADRRAEKSC EEASRSLVRR EYEAAVSHST DALVVLVPQA PSSGTPVPPS PPSLTATGPL
RSRALLYRIA AFLQLKNYDE ADEDCKHVLV EEIARGDGSL QASLRSMLLD GSLQEVASIL
SKALYGEPMN GIVAKDLTRL KMLLSEIEAI NRDMAPEYTD DQEEEVQDGW QFRPPPRGVT
SSEEYTLCKR YLEQGLCRYG AQCTSAHSQE ELMEWQKRYA SRLIRLKQQQ ESKHFTENYM
ETLIEKWMNS LSPEKVLSDC LEGVIVETSS SLSVTVTTKK SSHSWAFSLL CKPARKLYRI
ALLYDAHRPH FFITGVSAGE RLQAVPKGCQ EWTPGEDTAL AADNGLDNCL YKVAVSFSTE
IFGTFRQTVV FDFGSEPVLM QRIMVDAASI EDLEHLMAAR QQLLITAKRW DSSCKTIVEF
CPNETMAELE RSLLSRYQIP LSADQLFTQS VLDKTLTKDN YQARLHDLLY IEEIAQYKEV
SKFNIKVNLQ LVTSFMLTGI SVGAKYAQNG QLFARFKLTE TLSEDTLAGR LVMTKVNSVL
LLPLGREGIN SQPPPGVKER VYEAVIEEKT KEYIFLRICK DCCEELGLQP DREIQVELQF
QLNRLPLCEM HYALDRIKDN TILFPDVSLV PTIPWSPNRQ WDEQLDPRLN AKQKEAILAI
TTPISIPLPP ILIIGPYGTG KTFTLAQAVK HILRQDHSRV LICTHSNSAA DLYIKDYLHP
YVEAGNPHAR PLRVYFRNRW VKTVHPVVQQ YCLISSTQVT FQMPTREDIL RHRVVVVTLS
TSQYLCQLDL EPGLFTHILL DEAAQAMECE TIMPFALASK TTRIVLAGDH MQLSPFVYSE
FARERNLHVS LLDRLYEHYP PEFPCRILLC ENYRSHEAII NYTSELFYDG KLMASGKQPS
HKDFYPLTFF TARGEDVQEK NSTAYYNNAE VFEIVERVEE LRKKWPVAWG KLDEGSIGVV
SPYADQVFRI RAELRKKRMH EVSVERVLNV QGKQFRVLFL STVRTRHTCK HKQTAIKRKE
QLVEDSTEDL DYGFLSNYKL LNTAITRAQS LVAVVGDPIA LCSVGRCRKF WEHFISICHE
NSSLHGITFE QIKAQLEALE LKKTYVLNPL APEFIPRALR PLQGHHSSSQ ALHPHHHPHP
QHAQPATNKQ GPQQQQQQQQ QQSPPKGKHA NHTEHLPPDG YVQPNPAVLM GNPIRAFTPP
LGGTAAGMGK SPSPVQRIDP HTGASILYVP AVYGGNMVMS MPLPLPWPGY QNRFAVDPRI
MSHPAAMAYN FNLLQAQNRG SPIPYSGVGH PSPLGMGQPS PDKELQADPI RNGKLEGCPK
SEQSRLQTPE RKTADMKEKQ GDLDTGQGRS LDSQTDGLVG FPNALLHRKD PSAAQRPLNY
HLAPPNPAFP PHPASGRPFP PQYPVSRLPY RVGQPQHPGM AQQSQQQQQQ LSPAYTGGSH
NASFFSGPIP PHRAVQSPTL DGPESGGLEE MSSSIRTPMG HPGGHHPGLS QHNRVNSFGE
DGQDGNLGDG LDLQGPLALE ALSQQQQQAA RLGQWGEAAG PFLPGNVAFP LPQQLAHLAQ
PGMARIPHQL LRAASWGLSA NMEDEAVSSA STGPPYTRYP GLLREIPPQE QPEPREAAEM
QPPPQSRLLQ YRQSQSRASG DPSSSLATTS NHAGPFPSGP YAHDAGRNLL NDNLLNNPAL
QQQHPGNPLY NTGSYPHQPP THSASPPPSQ VKYLLQEAQW SHGGAASVSP PQQNHLLGNQ
GHGLPYGLPI MAHPSRQEQV HLMQLHHQHQ QQQQQQQQQQ QQQQQHYQQQ QQQQQQQHHQ
HQQSQGPDQE SYHPLSPRTS AATALHNVDE YEPRGPGRPL YQRRISSSYP DEPSPANTHN
ALSQQSQPCT SDPQDHPHPH IQHHQHPHAH YVYPSHDPWP SNGGGPGPFQ NIPCNGAGTL
AQHREILASK ALRQTEEQVK AEATAAQQTH PHSLNSLQHL GQFPPLMPNN KQQQQQQQQQ
QQQQPPPPPP PPPQAPTEPN QGAPNLNKPP TMSYASALRA PPKPRAVRPE QVKKNSDPLS
LLQELRIGSS NGSNGYYSYF K
//
