ID   A0A3B4UER1_SERDU        Unreviewed;       299 AA.
AC   A0A3B4UER1;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=Transmembrane BAX inhibitor motif containing 1b {ECO:0000313|Ensembl:ENSSDUP00000017144.1};
GN   Name=TMBIM1 {ECO:0000313|Ensembl:ENSSDUP00000017144.1};
OS   Seriola dumerili (Greater amberjack) (Caranx dumerili).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Carangaria; Carangiformes; Carangidae; Seriola.
OX   NCBI_TaxID=41447 {ECO:0000313|Ensembl:ENSSDUP00000017144.1, ECO:0000313|Proteomes:UP000261420};
RN   [1] {ECO:0000313|Ensembl:ENSSDUP00000017144.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the BI1 family. {ECO:0000256|RuleBase:RU004379}.
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DR   AlphaFoldDB; A0A3B4UER1; -.
DR   Ensembl; ENSSDUT00000017457.1; ENSSDUP00000017144.1; ENSSDUG00000012513.1.
DR   GeneTree; ENSGT01050000244890; -.
DR   OMA; GMWAAPG; -.
DR   Proteomes; UP000261420; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   CDD; cd10428; LFG_like; 1.
DR   InterPro; IPR006214; Bax_inhibitor_1-related.
DR   PANTHER; PTHR23291; BAX INHIBITOR-RELATED; 1.
DR   PANTHER; PTHR23291:SF35; PROTEIN LIFEGUARD 3; 1.
DR   Pfam; PF01027; Bax1-I; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU004379};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU004379};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU004379}.
FT   TRANSMEM        125..142
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU004379"
FT   TRANSMEM        149..172
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU004379"
FT   TRANSMEM        178..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU004379"
FT   TRANSMEM        209..233
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU004379"
FT   TRANSMEM        239..260
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU004379"
FT   TRANSMEM        272..293
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU004379"
FT   REGION          1..41
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   299 AA;  33329 MW;  7F3B5E6C412DE82A CRC64;
     MTTKIDSPPP YEDAVHHPKY GNYPHQPQHG SPLPPPPSYS PSPGMCPGPP GYWGREGVYP
     QAGMWSAPGF SPSGLPTTIP TLSAGVPPTN YHFAIPNSWE STSIRHAFIR KVRIFIIHHQ
     QSCHLSLHSV VYFLVYCILI CCKGPRRRFP WNLVIILFYV FVLIMKSVFY SYYETKAVFL
     AMGITAVVCI AVTIFCFQTK VDFTSCGGLL CIAAVLLMII GIVTAIVLSF QYVPWLHMLY
     AAIGAIVYTL FLVYNTQLLI GNRELAISPE EYIYGALSLY VDIVHIFLFI LQISGAATE
//