ID   A0A3B4UFZ6_SERDU        Unreviewed;       541 AA.
AC   A0A3B4UFZ6;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=Patched domain containing 1 {ECO:0000313|Ensembl:ENSSDUP00000016625.1};
GN   Name=PTCHD1 {ECO:0000313|Ensembl:ENSSDUP00000016625.1};
OS   Seriola dumerili (Greater amberjack) (Caranx dumerili).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Carangaria; Carangiformes; Carangidae; Seriola.
OX   NCBI_TaxID=41447 {ECO:0000313|Ensembl:ENSSDUP00000016625.1, ECO:0000313|Proteomes:UP000261420};
RN   [1] {ECO:0000313|Ensembl:ENSSDUP00000016625.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the patched family.
CC       {ECO:0000256|ARBA:ARBA00005585}.
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DR   AlphaFoldDB; A0A3B4UFZ6; -.
DR   STRING; 41447.ENSSDUP00000016625; -.
DR   Ensembl; ENSSDUT00000016931.1; ENSSDUP00000016625.1; ENSSDUG00000012151.1.
DR   GeneTree; ENSGT00940000157080; -.
DR   OMA; KAPQFAH; -.
DR   Proteomes; UP000261420; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 1.
DR   InterPro; IPR003392; Ptc/Disp.
DR   InterPro; IPR000731; SSD.
DR   PANTHER; PTHR10796:SF36; PATCHED DOMAIN-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR10796; PATCHED-RELATED; 1.
DR   Pfam; PF02460; Patched; 1.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 1.
DR   PROSITE; PS50156; SSD; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        25..43
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        55..75
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        157..174
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          1..81
FT                   /note="SSD"
FT                   /evidence="ECO:0000259|PROSITE:PS50156"
SQ   SEQUENCE   541 AA;  60741 MW;  668E956002AAF0A0 CRC64;
     MLSSWRRTRE DQHVKERVAS VFEDVMLRFS GSTMLHLMTL GLAASPLTNM EAVRLFCRTA
     ALAVTISYVY MLSFYSSCLV FTGYLETGYR HGCFCRRVPK PDRLDSKPAW YRCLIANNPN
     SHGHGHVANS THDSHLLLGC VRRCYGDWIT NTYVKPFVVL LYLVYISFGL MGFLQVTQGS
     DPSALVAMDT TTVLYTRAQQ RYFSSYSPVI GFYIYESAPY WNASVQRDLL EYAKGFQRIS
     WLEAYLNYLT DRNQSTSQSR ENFTRTLRHS FLREPQFAHF ADDIIFAERG QGEEPDVAAS
     RIFLVAKTTE NKREEMSVLL DTLRRLSLTS RVRFLIFNPS FVYLDRYAAA VSSPLRHSLL
     AVLFLLGLSS LAVVEPLVSV WLGLTLLSVQ FGVLGFMTLW GVELDCMSVL CLISALGHSA
     DCSGPLLCGF ASGRGESRTR WVRVALERHG VPSLQTLICY SAALVPVGSV RSNLTRTLFR
     CLTLTAGCSA LHTLAFLPTL LTFLPPSKSR GHRPGGDGQR QEVECVEMND STRVVDQITT
     V
//