ID A0A3B4UHH1_SERDU Unreviewed; 381 AA.
AC A0A3B4UHH1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Growth/differentiation factor 8-like {ECO:0000313|Ensembl:ENSSDUP00000017668.1};
OS Seriola dumerili (Greater amberjack) (Caranx dumerili).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=41447 {ECO:0000313|Ensembl:ENSSDUP00000017668.1, ECO:0000313|Proteomes:UP000261420};
RN [1] {ECO:0000313|Ensembl:ENSSDUP00000017668.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
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DR AlphaFoldDB; A0A3B4UHH1; -.
DR STRING; 41447.ENSSDUP00000017668; -.
DR Ensembl; ENSSDUT00000017991.1; ENSSDUP00000017668.1; ENSSDUG00000012917.1.
DR GeneTree; ENSGT00940000161872; -.
DR OMA; EYTMHFC; -.
DR OrthoDB; 3015718at2759; -.
DR Proteomes; UP000261420; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR CDD; cd19376; TGF_beta_GDF15; 1.
DR Gene3D; 2.60.120.970; -; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR015615; TGF-beta-rel.
DR InterPro; IPR017948; TGFb_CS.
DR PANTHER; PTHR11848:SF78; GROWTH_DIFFERENTIATION FACTOR 15; 1.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR PRINTS; PR00669; INHIBINA.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00250; TGF_BETA_1; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 3: Inferred from homology;
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354}; Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..381
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017391877"
FT DOMAIN 267..381
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
SQ SEQUENCE 381 AA; 42937 MW; FF679BBA2E2C49B7 CRC64;
MLRSRTLHRL IPCTLLLLVS LSSSGESRPH SEAHEGTPDV GGTESQKVLL LEAVKTGILS
SLGMDREPRP TQKATVQELK KMHQLYTDKL RVMRGNASQS MRETGQSTVS TVLFPATVEQ
VKVLWKEKHP QSDRHMQWHR AVFHKNPNIQ TELTLTRAEL MISRQIINKH TSAQPEVRRD
IKVKVNGRKS MNSPAWTQTD IPVHGNVSST QDVMLDISPE VEKWMRSDGG QALVVDVGMV
VLDRDALEAN PTISLELGLV QPEPAERRRR SNKEDDCDER GWCCRKSLAV SFKDIGWTDW
VVAPAEYTMH YCDGTCPHNY KPASMHTQVK SRLHQITKGG TPHPCCVPAT YEPMVLMHYD
SRGKLKLTPF DDLIVSKCHC A
//
