ID A0A3B4UI41_SERDU Unreviewed; 702 AA.
AC A0A3B4UI41;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Mbt domain containing 1 {ECO:0000313|Ensembl:ENSSDUP00000018284.1};
GN Name=MBTD1 {ECO:0000313|Ensembl:ENSSDUP00000018284.1};
OS Seriola dumerili (Greater amberjack) (Caranx dumerili).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=41447 {ECO:0000313|Ensembl:ENSSDUP00000018284.1, ECO:0000313|Proteomes:UP000261420};
RN [1] {ECO:0000313|Ensembl:ENSSDUP00000018284.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; A0A3B4UI41; -.
DR STRING; 41447.ENSSDUP00000018284; -.
DR Ensembl; ENSSDUT00000018616.1; ENSSDUP00000018284.1; ENSSDUG00000013361.1.
DR GeneTree; ENSGT00940000153840; -.
DR OMA; LHPIHKS; -.
DR Proteomes; UP000261420; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd20120; MBT_MBTD1_rpt1; 1.
DR CDD; cd20126; MBT_MBTD1_rpt3; 1.
DR CDD; cd20129; MBT_MBTD1_rpt4; 1.
DR Gene3D; 2.30.30.140; -; 4.
DR Gene3D; 3.30.60.160; -; 1.
DR InterPro; IPR004092; Mbt.
DR InterPro; IPR012313; Znf_FCS.
DR InterPro; IPR038603; Znf_FCS_sf.
DR PANTHER; PTHR12247:SF79; MBT DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR12247; POLYCOMB GROUP PROTEIN; 1.
DR Pfam; PF02820; MBT; 4.
DR Pfam; PF21319; zf-FCS_1; 1.
DR SMART; SM00561; MBT; 4.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 4.
DR PROSITE; PS51079; MBT; 4.
DR PROSITE; PS51024; ZF_FCS; 1.
PE 4: Predicted;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00367}.
FT DOMAIN 69..104
FT /note="FCS-type"
FT /evidence="ECO:0000259|PROSITE:PS51024"
FT REPEAT 165..269
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT REPEAT 277..373
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT REPEAT 375..480
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT REPEAT 488..584
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT REGION 1..54
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 582..702
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..24
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..46
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 582..602
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 603..618
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 658..677
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 678..702
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 702 AA; 79267 MW; 8A4148F4166986AC CRC64;
MEDTRDLAER TPRSERKRRD SFGMFDGYDS CSEESTSSSS SEDSEDEVVP SIPASLPIIK
NNGQVYTYPD GKAGMATCEM CGMVGVRDAF YSKTKRFCSV SCSRSYSSNS KKASILARLQ
GKPPTKKAKV LQKQPLMAKL AAYAQYQASQ QNQAKSKAVV PAESFDWGRY ICSNNTVGAP
VSCFKHAPMG LCWGDIEEGV RIEVLNSDTN LSTKVYWIAE IIKLAGFKAL LRYEGFDNDT
SKDFWCNLCI PEVHPVGWCA SSGKPLVPPK SIQHKYSNWK AFLVKRLTGA KTLPPDFNVK
VHENMQFPFK KLMRVEVVDK NYLCRTRVAL VEQVIGGRLR LVYEESQDGS DDFWCHMFSP
LIHNIGWSRS IGHRFKRSDI TKKMEGQVDA PAQLFQKVKD VDQTGDWFRD GMKLEAIDPL
NLSAICVATV RKVLADGYLM IGIDGSEAVD GSDWFCYHGT SPSIFPVGFC EINNIELTPP
RGYTKLPFKW FDYLRETGSI AAPVKLFNKE VPNHGFRQGM KLEAVDLMEP RLVCVATVTR
IVHRLLRIHF DGWEDEYDQW VDCESPDLYP VGWCQLTGYQ LQPPASQSNR DTPQSVPKQK
KKAQQYKGQK KKRKIPVGRR PFSQAGRRRS SFSGDEEQSP PPYPAQGPAR PRPRTHLHQT
HKSESLLRMK EETAEVDEFT FSQGTSDQES NGSGSYYIKQ EP
//
