ID   A0A3B4ULI8_SERDU        Unreviewed;       623 AA.
AC   A0A3B4ULI8;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=MPL proto-oncogene, thrombopoietin receptor {ECO:0000313|Ensembl:ENSSDUP00000019203.1};
OS   Seriola dumerili (Greater amberjack) (Caranx dumerili).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Carangaria; Carangiformes; Carangidae; Seriola.
OX   NCBI_TaxID=41447 {ECO:0000313|Ensembl:ENSSDUP00000019203.1, ECO:0000313|Proteomes:UP000261420};
RN   [1] {ECO:0000313|Ensembl:ENSSDUP00000019203.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B4ULI8; -.
DR   Ensembl; ENSSDUT00000019547.1; ENSSDUP00000019203.1; ENSSDUG00000013937.1.
DR   GeneTree; ENSGT00940000166530; -.
DR   OMA; WTECLAD; -.
DR   Proteomes; UP000261420; Unplaced.
DR   CDD; cd00063; FN3; 2.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 4.
DR   InterPro; IPR003961; FN3_dom.
DR   InterPro; IPR036116; FN3_sf.
DR   InterPro; IPR015152; Growth/epo_recpt_lig-bind.
DR   InterPro; IPR013783; Ig-like_fold.
DR   PANTHER; PTHR23037; CYTOKINE RECEPTOR; 1.
DR   PANTHER; PTHR23037:SF34; THROMBOPOIETIN RECEPTOR ISOFORM X1; 1.
DR   Pfam; PF09067; EpoR_lig-bind; 1.
DR   Pfam; PF00041; fn3; 1.
DR   SMART; SM00060; FN3; 2.
DR   SUPFAM; SSF49265; Fibronectin type III; 4.
DR   PROSITE; PS50853; FN3; 2.
PE   4: Predicted;
FT   DOMAIN          134..232
FT                   /note="Fibronectin type-III"
FT                   /evidence="ECO:0000259|PROSITE:PS50853"
FT   DOMAIN          325..420
FT                   /note="Fibronectin type-III"
FT                   /evidence="ECO:0000259|PROSITE:PS50853"
FT   REGION          494..518
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        498..518
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   623 AA;  70385 MW;  F8358D580CDBBCE3 CRC64;
     MYIWVVPRQL LRCRGCMPIG PLSSLDHVFL GLYLADVLLL KDKKDPKCFT RTGGDFTCFF
     ETADNRTYDL LYTAERYKRC VQRPEEGTYF HICSFPSGEV FLYTETQFEV VEHNTTTTLY
     NQTVYVEDHF LLDPPYNVSL YQNGHPGQLL VSWQTQAPTY CADVMYRIRY SSQGLGENTT
     ETKEVTHATV ILDSLVPGEE IEVQVAVKCG SSPSAGYWSS WSYLVRAMVP QSADDVSLMC
     YTSDLQNIIC QWNGSRYDVE KEYKLFYKIG LSEEWSQCIT DGKFTDLCRF RGDESRKVGV
     KLSSTQSPLS RAFYTQEFTL NKIIKTSPPS HLSGAWKKER LCLNWESPFL PLLAHLQYEV
     GYQTRESEAW MTVSLKGPET GTCLEVSKGN QYNIKVRAKP TGSIYSGHWS DWSDVVTGHN
     PTNLGMWFML FIPASMLIKL KQYFWPPVPN LDKVLQSFLT EINRQKWDPP LTTKQCTEET
     TASVVEIMSE DEISGLAKPS EESTQLLSPE GSLSSGEQVD GSLETKIFPD YVTLNKDSVI
     LCPKGNKYMY EKVGEKGVPG VGDDILLTCQ CSCSEGSVCV PPCLGKDFLN HSYVPLAEAA
     HRLEYRGTLE RGPGNLYTNL PCS
//