ID A0A3B4USP8_SERDU Unreviewed; 920 AA.
AC A0A3B4USP8;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Metabotropic glutamate receptor 7-like {ECO:0000313|Ensembl:ENSSDUP00000021418.1};
OS Seriola dumerili (Greater amberjack) (Caranx dumerili).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=41447 {ECO:0000313|Ensembl:ENSSDUP00000021418.1, ECO:0000313|Proteomes:UP000261420};
RN [1] {ECO:0000313|Ensembl:ENSSDUP00000021418.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 3 family.
CC {ECO:0000256|ARBA:ARBA00007242}.
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DR AlphaFoldDB; A0A3B4USP8; -.
DR STRING; 41447.ENSSDUP00000021418; -.
DR Ensembl; ENSSDUT00000021811.1; ENSSDUP00000021418.1; ENSSDUG00000015574.1.
DR GeneTree; ENSGT01030000234648; -.
DR OMA; CCWICEL; -.
DR Proteomes; UP000261420; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR CDD; cd15451; 7tmC_mGluR7; 1.
DR CDD; cd06376; PBP1_mGluR_groupIII; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR017979; GPCR_3_CS.
DR InterPro; IPR001786; GPCR_3_mGluR4.
DR InterPro; IPR000162; GPCR_3_mtglu_rcpt.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR24060; METABOTROPIC GLUTAMATE RECEPTOR; 1.
DR PANTHER; PTHR24060:SF98; METABOTROPIC GLUTAMATE RECEPTOR 7; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF07562; NCD3G; 1.
DR PRINTS; PR00248; GPCRMGR.
DR PRINTS; PR01054; MTABOTROPC4R.
DR PRINTS; PR00593; MTABOTROPICR.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00979; G_PROTEIN_RECEP_F3_1; 1.
DR PROSITE; PS00980; G_PROTEIN_RECEP_F3_2; 1.
DR PROSITE; PS00981; G_PROTEIN_RECEP_F3_3; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170}; Signal {ECO:0000256|SAM:SignalP};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..920
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017300855"
FT TRANSMEM 582..608
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 620..640
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 652..673
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 746..767
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 779..801
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 821..843
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 582..856
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
FT REGION 866..909
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 920 AA; 103027 MW; 0C22EA9F263AB064 CRC64;
MARPGVCVRL SSVWRVFWLM RTVVDFALPQ ETYAPHSIRT EGHLTLGGLF PVHARGTDGT
PCGDLKKENG IQRLEAMMYA LDQINQDEQL LPNITLGARV LDTCSRDTYA LEQSLTFVQA
LITKDTSDVR CTNGEPPVFV KPEKVVGVIG ASASSVSIMV ANILRLFQIP QISYASTAPE
LSDDRRYDFF SRVVPPDSFQ AQAMVDIIQA LGWSYVSTIA SEGSYGEKGV EAFTQLSKEA
GGICIAQSLK IPHNPKLEDY DKAIQQLLET QHSRAVVIFA SEEDIRGVLN ATKRANQVGH
FLWIGSDSWG AKSSPIHQLE DVAVGAVTIL PKRSSIKGFD EYFTALTLEN NRRNVWFAEF
WEENFDCRLL SASKREDSSR KCTGQERIGI NSKYEQEGKV QFVIDAVYAM AHALHNMHRD
LCPDHLGVCP QMESADGKTL LKYIRNTSFN GSAGTSVVFN KNGDAPGRYD LFQFQMTNSS
TPEYKMVGQW VETLQLRLEE LQWPDGEQDV PISVCSLPCK TGERKKRVKG MPCCWHCELC
DGYQYQYDET SCRLCAYNMR PNPNRTACQP IPIVKLEWHS PWAIIPVFLA MLGIIATIFV
MATFIRYNDT PIVRASGREL SYVLLTGIFL CYIITFLMIA KPDVAVCAFR RIFLGLGMCI
SYAALLTKTN RIYRIFEQGK QTVTAPRFIS PTSQIAITSS LICVQLLGVL VWFAVDPPNT
IVDYDEQKTI NPMLARGVLK CDITDLQIIC SLGYSILLMV TCTIYAIKTR DVPEDFNEAK
PIGFTMYTTC IVWLAFIPIF FGTAQSAEKL YIQTTTLTIS MNLSASVALG MLYMPKVYII
IFHPELNVQK RKRSFKAVVT AATMSSRLSQ KPNERPNGEA KTELCENPAA DPMSKCPSET
ITKPQSPMHM HHEPCSFKFI
//
