ID A0A3B4UYS8_SERDU Unreviewed; 753 AA.
AC A0A3B4UYS8;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Semaphorin-4E-like {ECO:0000313|Ensembl:ENSSDUP00000023631.1};
OS Seriola dumerili (Greater amberjack) (Caranx dumerili).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=41447 {ECO:0000313|Ensembl:ENSSDUP00000023631.1, ECO:0000313|Proteomes:UP000261420};
RN [1] {ECO:0000313|Ensembl:ENSSDUP00000023631.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the semaphorin family.
CC {ECO:0000256|ARBA:ARBA00009492}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR AlphaFoldDB; A0A3B4UYS8; -.
DR STRING; 41447.ENSSDUP00000023631; -.
DR Ensembl; ENSSDUT00000024070.1; ENSSDUP00000023631.1; ENSSDUG00000017179.1.
DR GeneTree; ENSGT00940000165728; -.
DR OMA; SLMVRED; -.
DR Proteomes; UP000261420; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030215; F:semaphorin receptor binding; IEA:InterPro.
DR GO; GO:0048468; P:cell development; IEA:UniProt.
DR GO; GO:0022008; P:neurogenesis; IEA:UniProt.
DR Gene3D; 3.30.1680.10; ligand-binding face of the semaphorins, domain 2; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR002165; Plexin_repeat.
DR InterPro; IPR016201; PSI.
DR InterPro; IPR001627; Semap_dom.
DR InterPro; IPR036352; Semap_dom_sf.
DR InterPro; IPR027231; Semaphorin.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR11036:SF135; SEMA DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11036; SEMAPHORIN; 1.
DR Pfam; PF01437; PSI; 1.
DR Pfam; PF01403; Sema; 1.
DR SMART; SM00423; PSI; 1.
DR SMART; SM00630; Sema; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF103575; Plexin repeat; 1.
DR SUPFAM; SSF101912; Sema domain; 1.
DR PROSITE; PS51004; SEMA; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 676..695
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 59..524
FT /note="Sema"
FT /evidence="ECO:0000259|PROSITE:PS51004"
FT REGION 711..753
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 711..726
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 727..746
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 753 AA; 83768 MW; E40A91CB4DDC1168 CRC64;
MPHLRLTLTS GNSIKSLQEQ NHDSAFQIKL NKNIMRPSVV LFYFLLIMSE GFETSNKPRR
SVSFQEMNVK QFEESGFGGL SSLMIRDDIR QLVVGARGKV LTLSLDDITK KTSEAKWSVS
SADKALCRMK GKDMKDCDNF IRMLHTMKDG KMLVCGTNAF NPACDHVIFK NGKLSLEGKK
QVGKGKVPFD PYERFASLMN GNTLYSAVSS NFLGTEVLFQ RHGLNLLKTE MKRSWFNEPT
MISISLVETS RNSDNGEDDN VFLFFTESAV EERHDNIRVS RIARVCKSDL GGERTLQKRW
TSFLKARLDC QFGDGGLPTL VQDVFLLRDL NNESIFYATL TSGSESSGGC SKSAVCAYKL
SDITQVFSGR FLTERESGRW DTYTGEEPFP HPGSCINDEM RANGVTTSLD LSDKTLLFVK
NHPLMEGVVA PMTGKPLLVQ TGTRFSKIIV DQVTSLDGRQ HQVMLIGTDS GWLQKAVRFD
GEDVRVIEEL QLFRAPQPID FLQLASKTGQ LYSGTSNIAV QVDVRDCSRY TSCNDCLLSR
DPYCGWDKIR GQCGSVVGAS TGSMIQSLSD GDITMCPTSG LKKKPAVVHI TVGIAQFLSC
SPSTNLPISW RFSDNILPPG PRHTVLRQGL IIRPSYSDAG FYTCETVETV KGKVHRETVV
RYLVRVQDTN TLVRSLKAAA ITLALLVVSL ILIMCRRIIC LKAKKQNNID CGNENSNNNQ
ETTVRPPFHH DQTEDRCTDE GRVQCGHGSD DVT
//
