ID   A0A3B4UYU7_SERDU        Unreviewed;       870 AA.
AC   A0A3B4UYU7;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Protocadherin alpha-C2-like {ECO:0000313|Ensembl:ENSSDUP00000023624.1};
OS   Seriola dumerili (Greater amberjack) (Caranx dumerili).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Carangaria; Carangiformes; Carangidae; Seriola.
OX   NCBI_TaxID=41447 {ECO:0000313|Ensembl:ENSSDUP00000023624.1, ECO:0000313|Proteomes:UP000261420};
RN   [1] {ECO:0000313|Ensembl:ENSSDUP00000023624.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004251};
CC       Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
CC       Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane
CC       protein {ECO:0000256|ARBA:ARBA00004479}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A3B4UYU7; -.
DR   Ensembl; ENSSDUT00000024062.1; ENSSDUP00000023624.1; ENSSDUG00000017069.1.
DR   GeneTree; ENSGT00940000160554; -.
DR   Proteomes; UP000261420; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR   CDD; cd11304; Cadherin_repeat; 6.
DR   Gene3D; 2.60.40.60; Cadherins; 6.
DR   InterPro; IPR002126; Cadherin-like_dom.
DR   InterPro; IPR015919; Cadherin-like_sf.
DR   InterPro; IPR031904; Cadherin_CBD.
DR   InterPro; IPR020894; Cadherin_CS.
DR   InterPro; IPR013164; Cadherin_N.
DR   PANTHER; PTHR24028; CADHERIN-87A; 1.
DR   PANTHER; PTHR24028:SF287; CADHERIN-RELATED NEURONAL RECEPTOR VARIABLE 1-RELATED; 1.
DR   Pfam; PF00028; Cadherin; 5.
DR   Pfam; PF08266; Cadherin_2; 1.
DR   Pfam; PF15974; Cadherin_tail; 1.
DR   PRINTS; PR00205; CADHERIN.
DR   SMART; SM00112; CA; 6.
DR   SUPFAM; SSF49313; Cadherin-like; 5.
DR   PROSITE; PS00232; CADHERIN_1; 3.
DR   PROSITE; PS50268; CADHERIN_2; 6.
PE   4: Predicted;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW   ProRule:PRU00043}; Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW   Membrane {ECO:0000256|SAM:Phobius}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Signal {ECO:0000256|ARBA:ARBA00022729};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        621..644
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          3..62
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          63..171
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          172..279
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          280..384
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          385..494
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          508..606
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   REGION          789..870
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        830..845
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   870 AA;  94962 MW;  EE5610B7B6D0785F CRC64;
     KCYFDINHET GVLSVSERID REEICPNTVK CSLNIEALMS NPRSLHRIEV VVNDINDNAP
     SFLEEISTID MSESSYIGER HPLPIAHDAD VGTNSVKTYK LNPNDYFSLD IQNTGDQSVS
     AELVLQKPLD REKQDVIELT LTAIDGGKPP KTGTLQIKVN VLDVNDNSPV FSKPLYKVQV
     VENTNIGTTL LTLNATDLDK GVNGELVYSF TESGRLNPDD KFALNDNTGV ITVKGNIDYE
     ENQAYEIRVQ ARDKGTPPRS AHCKVLFEVM DVNDNAPEIS VSSLMSPVKE DTEIGTAVAM
     VTITDKDGGK NGQTNCKLTG SVPFKLKSNY KNYYSLLVDG PLDRERVSQY NVSITATDEG
     TPSLSSISII TVQVSDVNDN PPRFLDSHIN IYVKENSPIG TTMHALTSLD LDLNENAKST
     YHLISSSPKT TQIASMVNIN SETGDIVSLQ SFNYEELKTF QFKVQATDSG VPPLSSNGTV
     NVFILDENDN NPTILAPYSE HGSVNSESIP YSAEVGYFVA KIRAVDADSG YNALLSYHLS
     DPKGNNLFRI GTSTGEIRTK RRMSDNDLKT HPLVVLVSDN GEPSLSATVS IEVVVVESTA
     DIQTQFRHVP IKEDSFSDLN LYRLIAIVSA SVIFLLSLFS LIAVKCHRKD GSFSRDSAPM
     ITTHPDGSWS YSKATQQYDV CFSSDTLKSD VVVFPAPFPP ADAELISING GDTFTRTQTL
     PNKEKPKAPN ADWRYSASLR AGGVSVHMEE SSVMQGAQGV LVQNWPTASS AAGEVSPPMG
     AGVDSNSWHF RYGPGGPGAP PQHLKPGEVP PEAFIIPGSP AIISIRQNQG GEDDKSDFIT
     FGKKEEAKKK KKKKKEKKDK KDKGKDDGDE
//