ID   A0A3B4V004_SERDU        Unreviewed;       624 AA.
AC   A0A3B4V004;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Kelch like family member 8 {ECO:0000313|Ensembl:ENSSDUP00000024118.1};
OS   Seriola dumerili (Greater amberjack) (Caranx dumerili).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Carangaria; Carangiformes; Carangidae; Seriola.
OX   NCBI_TaxID=41447 {ECO:0000313|Ensembl:ENSSDUP00000024118.1, ECO:0000313|Proteomes:UP000261420};
RN   [1] {ECO:0000313|Ensembl:ENSSDUP00000024118.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B4V004; -.
DR   STRING; 41447.ENSSDUP00000024118; -.
DR   Ensembl; ENSSDUT00000024571.1; ENSSDUP00000024118.1; ENSSDUG00000017411.1.
DR   GeneTree; ENSGT00940000157583; -.
DR   OMA; YRAAIKW; -.
DR   Proteomes; UP000261420; Unplaced.
DR   CDD; cd18448; BACK_KLHL8; 1.
DR   CDD; cd18238; BTB_POZ_KLHL8; 1.
DR   Gene3D; 1.25.40.420; -; 1.
DR   Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR   InterPro; IPR011705; BACK.
DR   InterPro; IPR017096; BTB-kelch_protein.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   InterPro; IPR006652; Kelch_1.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   PANTHER; PTHR24412:SF35; ACTIN-BINDING PROTEIN IPP; 1.
DR   PANTHER; PTHR24412; KELCH PROTEIN; 1.
DR   Pfam; PF07707; BACK; 1.
DR   Pfam; PF00651; BTB; 1.
DR   Pfam; PF01344; Kelch_1; 5.
DR   PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR   SMART; SM00875; BACK; 1.
DR   SMART; SM00225; BTB; 1.
DR   SMART; SM00612; Kelch; 6.
DR   SUPFAM; SSF117281; Kelch motif; 1.
DR   SUPFAM; SSF54695; POZ domain; 1.
DR   PROSITE; PS50097; BTB; 1.
PE   4: Predicted;
KW   Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          61..128
FT                   /note="BTB"
FT                   /evidence="ECO:0000259|PROSITE:PS50097"
FT   REGION          1..28
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        10..27
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   624 AA;  69461 MW;  FD3CB68597BDBDF6 CRC64;
     MAPGDVVPDH AKQLKSKDKR PGNRASKAEC EPDGSFVFEA HEAWKDFHNS LRHFYEVGEL
     CDVTLKVGSR LIPCHKLVLA CVIPYFRAMF LSEMSEAKQE LIEIKDFDGD AIQDLVHFAY
     SSKLTLTVDN VQPLLYAACI LQVELVARAC CEYMKAHFHP TNCLAVRTFA ESHNRVDLMD
     MADRYACEHF IEVVECEDFT CVSPQHLRTL LSSSELNIHS ETQVYNAAVK WLKANPQHHE
     AWLDQIMSQV RLPLLPVDFL TGTVAKDEMI KGNLSCRDLM DEARNYHLHL SNKVVPDFEY
     SIRTIPRKHT AGSTCMLMLG FEHITTAFIF LKCYVNSLIL RLWVLFCNSW FFGPEMNSRR
     RHVGVISVGG KVYAVGGHDG NEHLGNMEMF DPLTNKWMMK ASMNTKRRGI ALAALGGPIY
     AIGGLDDNSC FNDVERYDIE SDCWSAVAPM NTPRGGVGSV ALGSFVYAVG GNDGVASLSS
     VERFNPHLNK WTEVSEMGQR RAGNGVSKLN GCLYVVGGFD DNSPLSSVER FDPRMHRWEY
     VSELTTPRGG VGVATVMGRV FAVGGHNGNI YLNTVEAFEP RMNRWELVGS VSHCRAGAGV
     AVCLSHVSQI RDVGQGSSNV VNCM
//