ID A0A3B4V382_SERDU Unreviewed; 899 AA.
AC A0A3B4V382;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Metabotropic glutamate receptor 7-like {ECO:0000313|Ensembl:ENSSDUP00000024570.1};
GN Name=GRM7 {ECO:0000313|Ensembl:ENSSDUP00000024570.1};
OS Seriola dumerili (Greater amberjack) (Caranx dumerili).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=41447 {ECO:0000313|Ensembl:ENSSDUP00000024570.1, ECO:0000313|Proteomes:UP000261420};
RN [1] {ECO:0000313|Ensembl:ENSSDUP00000024570.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 3 family.
CC {ECO:0000256|ARBA:ARBA00007242}.
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DR AlphaFoldDB; A0A3B4V382; -.
DR STRING; 41447.ENSSDUP00000024570; -.
DR Ensembl; ENSSDUT00000025028.1; ENSSDUP00000024570.1; ENSSDUG00000017828.1.
DR GeneTree; ENSGT01030000234648; -.
DR OMA; SANRTSC; -.
DR Proteomes; UP000261420; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR CDD; cd15451; 7tmC_mGluR7; 1.
DR CDD; cd06376; PBP1_mGluR_groupIII; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR017979; GPCR_3_CS.
DR InterPro; IPR001883; GPCR_3_mGluR7.
DR InterPro; IPR000162; GPCR_3_mtglu_rcpt.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR24060; METABOTROPIC GLUTAMATE RECEPTOR; 1.
DR PANTHER; PTHR24060:SF98; METABOTROPIC GLUTAMATE RECEPTOR 7; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF07562; NCD3G; 1.
DR PRINTS; PR00248; GPCRMGR.
DR PRINTS; PR01057; MTABOTROPC7R.
DR PRINTS; PR00593; MTABOTROPICR.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00979; G_PROTEIN_RECEP_F3_1; 1.
DR PROSITE; PS00980; G_PROTEIN_RECEP_F3_2; 1.
DR PROSITE; PS00981; G_PROTEIN_RECEP_F3_3; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170}; Signal {ECO:0000256|SAM:SignalP};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..32
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 33..899
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017481875"
FT TRANSMEM 585..611
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 623..643
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 655..676
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 749..770
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 782..804
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 824..846
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 585..859
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
FT REGION 872..899
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 899 AA; 100336 MW; 9384E74340CAEA60 CRC64;
MGRHSNNLPQ LKPCFTFRVL WMVQAFLDLA GSQEIYAPHS IRVEGDVTLG GLFPVHARGV
PGIPCGDIKK ENGIHRLEAM MYALDQINGD EDLLPNVTLG ARILDTCSRD TYALEQSLTF
VQALIQKDTS DVRCTNGEPP VFVKPEKVVG VIGASASSVS IMVANILRLF QIPQISYAST
APELSDDRRY DFFSRVVPPD SFQAQAMVDI VKAMGWNYVS TVASEGSYGE KGVDAFMQLS
REAGGICIAQ SLKIPHDHKP SDFDKIIRLL LDTRYARAVI LFASDEDIRG ILNASKRADQ
VGHFMWIGSD SWGAKNSPIH QLEDAAVGAV TILPKRATIS GFDAYFTSRT LENNRRNVWF
AEYWEENFNC KLMSSSKKDE SSRKCTGQER IGIDSKYEQE GKVQFVIDAV YAMAHALHNM
QRDLCPENSG ICPEMDLAGG KKLLKYIRSV SFNGSAGTSV TFNRNGDAPG RYDLFQYQWN
NISGPGYRVI GQWTENLQLN IEDMQWPRGE QEIPSSVCSL PCKTGERKKV VKGMPCCWHC
EPCDGYQYQY NEFTCKLCSY NMRPNANRTS CQPIPIIKLE WHSPWAVIPV FLAMLGIIAT
IFVMATFIRY NDTPIVRASG RELSYVLLTG IFLCYIITFL MIAKPDVGVC SFRRIFLGLG
MCISYAALLT KTNRIYRIFE QGKKSVTAPR LISPTSQLAI TSSLISVQLL GVLIWFGVDP
PNTIIDYDEQ KTINPDLARG VLKCDITDLQ IICSLGYSIL LMVTCTVYAI KTRGVPENFN
EAKPIGFTMY TTCIVWLAFI PIFFGTAQSA EKLYIQTTTL TISMNLSASV ALGMLYMPKV
YVIIFHPELN VQKRKRSFKA VVTAATMSSR LSHKASDRPN GEAKTELCEN VDPNSKYSV
//
