ID   A0A3B4V4Z7_SERDU        Unreviewed;       498 AA.
AC   A0A3B4V4Z7;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=Fascin {ECO:0000256|PIRNR:PIRNR005682};
GN   Name=FSCN1 {ECO:0000313|Ensembl:ENSSDUP00000025786.1};
OS   Seriola dumerili (Greater amberjack) (Caranx dumerili).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Carangaria; Carangiformes; Carangidae; Seriola.
OX   NCBI_TaxID=41447 {ECO:0000313|Ensembl:ENSSDUP00000025786.1, ECO:0000313|Proteomes:UP000261420};
RN   [1] {ECO:0000313|Ensembl:ENSSDUP00000025786.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC       {ECO:0000256|ARBA:ARBA00004245, ECO:0000256|PIRNR:PIRNR005682}.
CC   -!- SIMILARITY: Belongs to the fascin family.
CC       {ECO:0000256|ARBA:ARBA00007415, ECO:0000256|PIRNR:PIRNR005682}.
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DR   AlphaFoldDB; A0A3B4V4Z7; -.
DR   STRING; 41447.ENSSDUP00000025786; -.
DR   Ensembl; ENSSDUT00000026253.1; ENSSDUP00000025786.1; ENSSDUG00000018700.1.
DR   GeneTree; ENSGT00950000183157; -.
DR   OMA; NIFSMTR; -.
DR   OrthoDB; 5484756at2759; -.
DR   Proteomes; UP000261420; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR   GO; GO:0030674; F:protein-macromolecule adaptor activity; IEA:InterPro.
DR   GO; GO:0007015; P:actin filament organization; IEA:InterPro.
DR   CDD; cd00257; Fascin; 4.
DR   Gene3D; 2.80.10.50; -; 4.
DR   InterPro; IPR008999; Actin-crosslinking.
DR   InterPro; IPR010431; Fascin.
DR   InterPro; IPR022768; Fascin-domain.
DR   InterPro; IPR024703; Fascin_metazoans.
DR   PANTHER; PTHR10551; FASCIN; 1.
DR   PANTHER; PTHR10551:SF23; FASCIN; 1.
DR   Pfam; PF06268; Fascin; 4.
DR   PIRSF; PIRSF005682; Fascin; 1.
DR   SUPFAM; SSF50405; Actin-crosslinking proteins; 4.
PE   3: Inferred from homology;
KW   Actin-binding {ECO:0000256|ARBA:ARBA00023203,
KW   ECO:0000256|PIRNR:PIRNR005682};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|PIRNR:PIRNR005682};
KW   Cytoskeleton {ECO:0000256|ARBA:ARBA00023212,
KW   ECO:0000256|PIRNR:PIRNR005682}.
FT   DOMAIN          25..138
FT                   /note="Fascin"
FT                   /evidence="ECO:0000259|Pfam:PF06268"
FT   DOMAIN          147..258
FT                   /note="Fascin"
FT                   /evidence="ECO:0000259|Pfam:PF06268"
FT   DOMAIN          271..381
FT                   /note="Fascin"
FT                   /evidence="ECO:0000259|Pfam:PF06268"
FT   DOMAIN          395..498
FT                   /note="Fascin"
FT                   /evidence="ECO:0000259|Pfam:PF06268"
SQ   SEQUENCE   498 AA;  55245 MW;  D1B44EE01A3655B1 CRC64;
     MTTNGASNGT SDMLQIQFGL INCGNKYLTA ETFGFKINAS ATSMKKKQIW TLEQSGDDSS
     GNVFHLKSHL GRYIAADKDG NVTGDSETPG PECRFIITAH DDGRWSLQSE PHGRYLGGTE
     DRIICFAQTA SVAEKWSVHI AMHPQVNIFS LTRKRYAHLS SKVDEIAIDR DVPWGVDSMI
     TLVFREQRYH LQTSDNRFLR NDGALVATTD KSTGYTLEFR SGKVAFRDCS GKYLAPSGPS
     GTMKSGKSAR VGKDELFVLE QSHPQVVLTA ANERNVSTRQ GMDLSANQDE EGDQEVFQVE
     ICRENRKCAF RTAAGKYWTL TANGGLQCTA STKSANCYFD IEWRGKRLTL RAANGKYVAA
     KKNGQLAATM DSAGETEEFI MKLINRPIIV LRGEHGFIGC RKVTGTLDSN RSSYDYFTLE
     FRDGAYSLQD STGKYWMVGN EQSVVSSSDT PVDFLFEFCD YNKLAVRHGA DGKYLRGDHA
     GVLKANADDL ETATLWEY
//